Metal-phenolic network biointerface-mediated cell regulation for bone tissue regeneration
Bone tissue regeneration presents a significant challenge in clinical treatment due to inadequate coordination between implant materials and reparative cells at the biomaterial-bone interfaces. This gap underscores the necessity of enhancing interaction modulation between cells and biomaterials, whi...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Materials Today Bio |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006424004617 |
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| author | Ying Wang Zhibang Li Ruiqing Yu Yi Chen Danyang Wang Weiwei Zhao Shaohua Ge Hong Liu Jianhua Li |
| author_facet | Ying Wang Zhibang Li Ruiqing Yu Yi Chen Danyang Wang Weiwei Zhao Shaohua Ge Hong Liu Jianhua Li |
| author_sort | Ying Wang |
| collection | DOAJ |
| description | Bone tissue regeneration presents a significant challenge in clinical treatment due to inadequate coordination between implant materials and reparative cells at the biomaterial-bone interfaces. This gap underscores the necessity of enhancing interaction modulation between cells and biomaterials, which is a crucial focus in bone tissue engineering. Metal-polyphenolic networks (MPN) are novel inorganic-organic hybrid complexes that are formed through coordination interactions between phenolic ligands and metal ions. These networks provide a multifunctional platform for biomedical applications, with the potential for tailored design and modifications. Despite advances in understanding MPN and their role in bone tissue regeneration, a comprehensive overview of the related mechanisms is lacking. Here, we address this gap by focusing on MPN biointerface-mediated cellular regulatory mechanisms during bone regeneration. We begin by reviewing the natural healing processes of bone defects, followed by a detailed examination of MPN, including their constituents and distinctive characteristics. We then explore the regulatory influence of MPN biointerfaces on key cellular activities during bone regeneration. Additionally, we illustrate their primary applications in addressing inflammatory bone loss, regenerating critical-size bone defects, and enhancing implant-bone integration. In conclusion, this review elucidates how MPN-based interfaces facilitate effective bone tissue regeneration, advancing our understanding of material interface-mediated cellular control and the broader field of tissue engineering. |
| format | Article |
| id | doaj-art-01a3410f042641c19273fd041aa7b622 |
| institution | Kabale University |
| issn | 2590-0064 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj-art-01a3410f042641c19273fd041aa7b6222025-01-17T04:52:06ZengElsevierMaterials Today Bio2590-00642025-02-0130101400Metal-phenolic network biointerface-mediated cell regulation for bone tissue regenerationYing Wang0Zhibang Li1Ruiqing Yu2Yi Chen3Danyang Wang4Weiwei Zhao5Shaohua Ge6Hong Liu7Jianhua Li8Department of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, ChinaDepartment of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, ChinaDepartment of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, ChinaDepartment of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, ChinaDepartment of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, ChinaDepartment of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China; Corresponding author.Department of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, ChinaState Key Laboratory of Crystal Materials, Shandong University, Jinan, Shandong, 250100, ChinaDepartment of Biomaterials, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China; Corresponding author.Bone tissue regeneration presents a significant challenge in clinical treatment due to inadequate coordination between implant materials and reparative cells at the biomaterial-bone interfaces. This gap underscores the necessity of enhancing interaction modulation between cells and biomaterials, which is a crucial focus in bone tissue engineering. Metal-polyphenolic networks (MPN) are novel inorganic-organic hybrid complexes that are formed through coordination interactions between phenolic ligands and metal ions. These networks provide a multifunctional platform for biomedical applications, with the potential for tailored design and modifications. Despite advances in understanding MPN and their role in bone tissue regeneration, a comprehensive overview of the related mechanisms is lacking. Here, we address this gap by focusing on MPN biointerface-mediated cellular regulatory mechanisms during bone regeneration. We begin by reviewing the natural healing processes of bone defects, followed by a detailed examination of MPN, including their constituents and distinctive characteristics. We then explore the regulatory influence of MPN biointerfaces on key cellular activities during bone regeneration. Additionally, we illustrate their primary applications in addressing inflammatory bone loss, regenerating critical-size bone defects, and enhancing implant-bone integration. In conclusion, this review elucidates how MPN-based interfaces facilitate effective bone tissue regeneration, advancing our understanding of material interface-mediated cellular control and the broader field of tissue engineering.http://www.sciencedirect.com/science/article/pii/S2590006424004617Metal-polyphenolic networksBone tissue regenerationBiointerfaceStem cellsImmunoregulation |
| spellingShingle | Ying Wang Zhibang Li Ruiqing Yu Yi Chen Danyang Wang Weiwei Zhao Shaohua Ge Hong Liu Jianhua Li Metal-phenolic network biointerface-mediated cell regulation for bone tissue regeneration Materials Today Bio Metal-polyphenolic networks Bone tissue regeneration Biointerface Stem cells Immunoregulation |
| title | Metal-phenolic network biointerface-mediated cell regulation for bone tissue regeneration |
| title_full | Metal-phenolic network biointerface-mediated cell regulation for bone tissue regeneration |
| title_fullStr | Metal-phenolic network biointerface-mediated cell regulation for bone tissue regeneration |
| title_full_unstemmed | Metal-phenolic network biointerface-mediated cell regulation for bone tissue regeneration |
| title_short | Metal-phenolic network biointerface-mediated cell regulation for bone tissue regeneration |
| title_sort | metal phenolic network biointerface mediated cell regulation for bone tissue regeneration |
| topic | Metal-polyphenolic networks Bone tissue regeneration Biointerface Stem cells Immunoregulation |
| url | http://www.sciencedirect.com/science/article/pii/S2590006424004617 |
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