TGF-β expressed by M2 macrophages promotes wound healing by inhibiting TSG-6 expression by mesenchymal stem cells.

TGF-β expressed by M2 macrophages promotes wound healing by inhibiting TSG-6 expression by mesenchymal stem cells.

Wound healing involves the collaboration of multiple cells, including macrophages and fibroblasts, and requires the coordination of cytokines, growth factors, and matrix proteins to regulate the repair response. In this study, we investigated how M2 macrophages regulate expression of the anti-fibrot...

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Main Authors: Young Woo Eom, Ju-Eun Hong, Pil Young Jung, Yongdae Yoon, Sang-Hyeon Yoo, Jiyun Hong, Ki-Jong Rhee, Bhupendra Regmi, Saher Fatima, Moon Young Kim, Soon Koo Baik, Hoon Ryu, Hye Youn Kwon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0316692
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