Impaired modulation of the trigeminal caudal nucleus by the locus coeruleus in diabetic mice: the role of GABAergic and glycinergic neurons

Impaired modulation of the trigeminal caudal nucleus by the locus coeruleus in diabetic mice: the role of GABAergic and glycinergic neurons

The trigeminal system plays a crucial role in processing somatosensory information, and its modulation is essential for maintaining sensory homeostasis. This study investigates the inhibitory modulation of trigeminal somatosensory responses by the locus coeruleus (LC), which is involved in numerous...

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Bibliographic Details
Main Authors: Alberto Mesa-Lombardo, Nuria García-Magro, Angel Nuñez, Yasmina B. Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neuroanatomy
Subjects:
noradrenergic receptors
GABAergic neurons
glycinergic neurons
pain
diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2025.1600026/full
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