Synergistic Effect of Conditioned Medium from Amniotic Membrane Mesenchymal Stromal Cells Combined with Paclitaxel on Ovarian Cancer Cell Viability and Migration in 2D and 3D In Vitro Models

Synergistic Effect of Conditioned Medium from Amniotic Membrane Mesenchymal Stromal Cells Combined with Paclitaxel on Ovarian Cancer Cell Viability and Migration in 2D and 3D In Vitro Models

<b>Background:</b> Ovarian cancer accounts for more deaths than any other cancer of the female reproductive system. Despite standard care, recurrence due to tumor spread and chemoresistance is common, highlighting the need for novel therapies. Mesenchymal stromal cells from the human amn...

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Main Authors: Paola Chiodelli, Patrizia Bonassi Signoroni, Elisa Scalvini, Serafina Farigu, Elisabetta Giuzzi, Alice Paini, Andrea Papait, Francesca Romana Stefani, Antonietta Rosa Silini, Ornella Parolini
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
human amniotic mesenchymal stromal cell
amniotic membrane
ovarian cancer
3D model
paclitaxel
Online Access:https://www.mdpi.com/1999-4923/17/4/420
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