Dimensional Coupling in Synergistic Bio‐Nano Growth Systems
ABSTRACT The growth of hybrid nanostructures composed of inorganic materials and biomolecules has garnered significant attention due to their potential applications across diverse fields. However, the mutual competition mechanisms at the bio‐nano interface, particularly from the perspective of dimen...
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| Format: | Article |
| Language: | English |
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Wiley
2025-06-01
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| Series: | MedComm – Biomaterials and Applications |
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| Online Access: | https://doi.org/10.1002/mba2.70008 |
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| author | Ming Yuan Xinmin Zhao Jun Guo Feng Zhang |
| author_facet | Ming Yuan Xinmin Zhao Jun Guo Feng Zhang |
| author_sort | Ming Yuan |
| collection | DOAJ |
| description | ABSTRACT The growth of hybrid nanostructures composed of inorganic materials and biomolecules has garnered significant attention due to their potential applications across diverse fields. However, the mutual competition mechanisms at the bio‐nano interface, particularly from the perspective of dimensional evolution, have been seldom explored. Herein, we ascertain a distinct dimensional evolution by establishing a synergistic growth model system that hybridizes protein fibrils and gold nanostructures. Specifically, ionic gold precursors increase in dimension from zero to three dimensions, while amyloid proteins conversely decrease from three to one dimension. This dimensional evolution has important implications for reducing the bio‐nano interface and potentially limiting harmful coupling between biomolecules and inorganic nanomaterials, despite the fact that they can act as templates or scaffolds for each other to promote dimensional evolution. The findings highlight the potential of these hybrid systems in biomedical applications, such as targeted drug delivery and bioimaging, by leveraging the unique dimensional coupling between proteins and gold nanostructures. This work provides insights into the complex bio‐nano interactions between organisms and inorganic materials, emphasizing the need for precise and rational design of bio‐nano systems suitable for clinical applications. |
| format | Article |
| id | doaj-art-019fb5ab4cff403e8effcf532b5b41fd |
| institution | DOAJ |
| issn | 2769-643X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | MedComm – Biomaterials and Applications |
| spelling | doaj-art-019fb5ab4cff403e8effcf532b5b41fd2025-08-20T03:23:27ZengWileyMedComm – Biomaterials and Applications2769-643X2025-06-0142n/an/a10.1002/mba2.70008Dimensional Coupling in Synergistic Bio‐Nano Growth SystemsMing Yuan0Xinmin Zhao1Jun Guo2Feng Zhang3School of Chemistry and Life Sciences Chifeng University Chifeng ChinaTerahertz Technology Innovation Research Institute, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Shanghai Key Lab of Modern Optical System University of Shanghai for Science and Technology Shanghai ChinaWenzhou Institute University of Chinese Academy of Sciences, Wenzhou Wenzhou ChinaTerahertz Technology Innovation Research Institute, Terahertz Spectrum and Imaging Technology Cooperative Innovation Center, Shanghai Key Lab of Modern Optical System University of Shanghai for Science and Technology Shanghai ChinaABSTRACT The growth of hybrid nanostructures composed of inorganic materials and biomolecules has garnered significant attention due to their potential applications across diverse fields. However, the mutual competition mechanisms at the bio‐nano interface, particularly from the perspective of dimensional evolution, have been seldom explored. Herein, we ascertain a distinct dimensional evolution by establishing a synergistic growth model system that hybridizes protein fibrils and gold nanostructures. Specifically, ionic gold precursors increase in dimension from zero to three dimensions, while amyloid proteins conversely decrease from three to one dimension. This dimensional evolution has important implications for reducing the bio‐nano interface and potentially limiting harmful coupling between biomolecules and inorganic nanomaterials, despite the fact that they can act as templates or scaffolds for each other to promote dimensional evolution. The findings highlight the potential of these hybrid systems in biomedical applications, such as targeted drug delivery and bioimaging, by leveraging the unique dimensional coupling between proteins and gold nanostructures. This work provides insights into the complex bio‐nano interactions between organisms and inorganic materials, emphasizing the need for precise and rational design of bio‐nano systems suitable for clinical applications.https://doi.org/10.1002/mba2.70008amyloid fibrilsbio‐nano interfacedimensional evolutionhybrid nanostructuresynergistic growth |
| spellingShingle | Ming Yuan Xinmin Zhao Jun Guo Feng Zhang Dimensional Coupling in Synergistic Bio‐Nano Growth Systems MedComm – Biomaterials and Applications amyloid fibrils bio‐nano interface dimensional evolution hybrid nanostructure synergistic growth |
| title | Dimensional Coupling in Synergistic Bio‐Nano Growth Systems |
| title_full | Dimensional Coupling in Synergistic Bio‐Nano Growth Systems |
| title_fullStr | Dimensional Coupling in Synergistic Bio‐Nano Growth Systems |
| title_full_unstemmed | Dimensional Coupling in Synergistic Bio‐Nano Growth Systems |
| title_short | Dimensional Coupling in Synergistic Bio‐Nano Growth Systems |
| title_sort | dimensional coupling in synergistic bio nano growth systems |
| topic | amyloid fibrils bio‐nano interface dimensional evolution hybrid nanostructure synergistic growth |
| url | https://doi.org/10.1002/mba2.70008 |
| work_keys_str_mv | AT mingyuan dimensionalcouplinginsynergisticbionanogrowthsystems AT xinminzhao dimensionalcouplinginsynergisticbionanogrowthsystems AT junguo dimensionalcouplinginsynergisticbionanogrowthsystems AT fengzhang dimensionalcouplinginsynergisticbionanogrowthsystems |