Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agents
To investigate the regioselectivity of lipase-catalyzed synthesis of important sugar-laurate esters and their functionalities as emulsifiers and antimicrobial agents, glucose, galactose, mannose, maltose and trehalose were used. 6-O-lauryl glucose (Glu-L), 6-O-lauryl galactose (Gal-L), 6-O-lauryl ma...
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Elsevier
2025-04-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157525002305 |
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| author | Kangzi Ren Guilin Chen Ziyi Zhang Zhao Long Bo Zhou Wenfang Han Qinlu Lin |
| author_facet | Kangzi Ren Guilin Chen Ziyi Zhang Zhao Long Bo Zhou Wenfang Han Qinlu Lin |
| author_sort | Kangzi Ren |
| collection | DOAJ |
| description | To investigate the regioselectivity of lipase-catalyzed synthesis of important sugar-laurate esters and their functionalities as emulsifiers and antimicrobial agents, glucose, galactose, mannose, maltose and trehalose were used. 6-O-lauryl glucose (Glu-L), 6-O-lauryl galactose (Gal-L), 6-O-lauryl mannose (Man-L), 6′-O-lauryl maltose (Mal-L) and 6-O-lauryl trehalose/6’-O-lauryl trehalose (Tre-L) were synthesized using lipase from Candida antarctica. The Glu-L and Man-L achieved the highest yields (65.49 % and 58.16 %, respectively). The synthesized esters produced smaller-particle-size (1.9–3.1 μm), but less stable emulsions than the commercial sucrose esters (4.2–8.1 μm). The zeta-potential data revealed Man-L and Gal-L had higher surface coverage than the Glu-L on the oil droplets, while the Mal-L and Tre-L had similar surface coverage. The Man-L, Mal-L and Tre-L demonstrated the superior foamability and foam stability. The Gal-L, Man-L, Mal-L, and Tre-L inhibited E.coli 12024 (MIC 1–4 mg/mL), while only Man-L, Mal-L, and Tre-L inhibited B.subtilis 5009 (MIC 0.5–2.0 mg/mL). |
| format | Article |
| id | doaj-art-019f54f87bad44fcb854f3e0821c337d |
| institution | OA Journals |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-019f54f87bad44fcb854f3e0821c337d2025-08-20T02:30:50ZengElsevierFood Chemistry: X2590-15752025-04-012710238310.1016/j.fochx.2025.102383Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agentsKangzi Ren0Guilin Chen1Ziyi Zhang2Zhao Long3Bo Zhou4Wenfang Han5Qinlu Lin6College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China; National Engineering Research Center of Rice and Byproduct Deep Processing, 498 South Shaoshan Road, Hunan 419994, ChinaCollege of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China; National Engineering Research Center of Rice and Byproduct Deep Processing, 498 South Shaoshan Road, Hunan 419994, ChinaCollege of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China; National Engineering Research Center of Rice and Byproduct Deep Processing, 498 South Shaoshan Road, Hunan 419994, ChinaCollege of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China; National Engineering Research Center of Rice and Byproduct Deep Processing, 498 South Shaoshan Road, Hunan 419994, ChinaCollege of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China; National Engineering Research Center of Rice and Byproduct Deep Processing, 498 South Shaoshan Road, Hunan 419994, ChinaCollege of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China; National Engineering Research Center of Rice and Byproduct Deep Processing, 498 South Shaoshan Road, Hunan 419994, ChinaCollege of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China; National Engineering Research Center of Rice and Byproduct Deep Processing, 498 South Shaoshan Road, Hunan 419994, China; Corresponding author at: College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China.To investigate the regioselectivity of lipase-catalyzed synthesis of important sugar-laurate esters and their functionalities as emulsifiers and antimicrobial agents, glucose, galactose, mannose, maltose and trehalose were used. 6-O-lauryl glucose (Glu-L), 6-O-lauryl galactose (Gal-L), 6-O-lauryl mannose (Man-L), 6′-O-lauryl maltose (Mal-L) and 6-O-lauryl trehalose/6’-O-lauryl trehalose (Tre-L) were synthesized using lipase from Candida antarctica. The Glu-L and Man-L achieved the highest yields (65.49 % and 58.16 %, respectively). The synthesized esters produced smaller-particle-size (1.9–3.1 μm), but less stable emulsions than the commercial sucrose esters (4.2–8.1 μm). The zeta-potential data revealed Man-L and Gal-L had higher surface coverage than the Glu-L on the oil droplets, while the Mal-L and Tre-L had similar surface coverage. The Man-L, Mal-L and Tre-L demonstrated the superior foamability and foam stability. The Gal-L, Man-L, Mal-L, and Tre-L inhibited E.coli 12024 (MIC 1–4 mg/mL), while only Man-L, Mal-L, and Tre-L inhibited B.subtilis 5009 (MIC 0.5–2.0 mg/mL).http://www.sciencedirect.com/science/article/pii/S2590157525002305Sugar esterLauric acidLipase-catalyzed synthesisEmulsifiersFoamAntibacterial |
| spellingShingle | Kangzi Ren Guilin Chen Ziyi Zhang Zhao Long Bo Zhou Wenfang Han Qinlu Lin Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agents Food Chemistry: X Sugar ester Lauric acid Lipase-catalyzed synthesis Emulsifiers Foam Antibacterial |
| title | Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agents |
| title_full | Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agents |
| title_fullStr | Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agents |
| title_full_unstemmed | Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agents |
| title_short | Enzymatic synthesis of some sugar-lauric acid esters by lipase from Candida antarctica and their functionalities as emulsifiers and antibacterial agents |
| title_sort | enzymatic synthesis of some sugar lauric acid esters by lipase from candida antarctica and their functionalities as emulsifiers and antibacterial agents |
| topic | Sugar ester Lauric acid Lipase-catalyzed synthesis Emulsifiers Foam Antibacterial |
| url | http://www.sciencedirect.com/science/article/pii/S2590157525002305 |
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