Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria
Background: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide. There is little information on the prevalence of HSV-2 in Nigeria. Methodology: Specimens were collected from 162 volu...
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The Journal of Infection in Developing Countries
2010-05-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/567 |
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| author | Yusuf A. Agabi Edmund B. Banwat John D Mawak Patricia M Lar Nanma Dashe Michael M Dashen Moses P Adoga Felicia Y Agabi Hashimu Zakari |
| author_facet | Yusuf A. Agabi Edmund B. Banwat John D Mawak Patricia M Lar Nanma Dashe Michael M Dashen Moses P Adoga Felicia Y Agabi Hashimu Zakari |
| author_sort | Yusuf A. Agabi |
| collection | DOAJ |
| description |
Background: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide. There is little information on the prevalence of HSV-2 in Nigeria.
Methodology: Specimens were collected from 162 volunteers attending Jos University Teaching Hospital and tested for HSV-2 antibodies using HSV-2 Type specific IgG EIA test kit (Globalemed LLC Alexandria VA, USA). Data were analyzed using SPSS version 13.0. P values ≤ 0.05 were considered significant. numbr
Results: Out of the 162 individuals tested, 141 (87.0%) were HSV-2 positive. Infected individuals were more likely to be male than female (92.8% versus 86.4%; P > 0.05). There were high rates of infection in all age groups, and the prevalence increased with age. However, multivariate logistic regression analysis showed that HSV-2 prevalence was not significantly associated with increasing age, sex, marital status, occupation, educational status, and number of sex partners (P > 0.05).
Conclusions: The results highlight the potential public health impact of HSV-2 in Nigeria where anti-HSV-2 testing is not generally performed in all populations, especially considering the risk of neonatal transmission and the attendant complications at birth.
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| format | Article |
| id | doaj-art-019d05fc782742e9bc104e1572ef425e |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2010-05-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-019d05fc782742e9bc104e1572ef425e2025-08-20T02:27:18ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802010-05-0140910.3855/jidc.567Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, NigeriaYusuf A. Agabi0Edmund B. Banwat1John D Mawak2Patricia M Lar3Nanma Dashe4Michael M Dashen5Moses P Adoga6Felicia Y Agabi7Hashimu Zakari8University of JOSUniversity of JosUniversity of JosUniversity of JosUniversity of JosUniversityb of JosInnovative Biotech. Nigeria LtdDalhatu Araf Specialist Hospital Lafia, NigeriaUniversity of Jos Background: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide. There is little information on the prevalence of HSV-2 in Nigeria. Methodology: Specimens were collected from 162 volunteers attending Jos University Teaching Hospital and tested for HSV-2 antibodies using HSV-2 Type specific IgG EIA test kit (Globalemed LLC Alexandria VA, USA). Data were analyzed using SPSS version 13.0. P values ≤ 0.05 were considered significant. numbr Results: Out of the 162 individuals tested, 141 (87.0%) were HSV-2 positive. Infected individuals were more likely to be male than female (92.8% versus 86.4%; P > 0.05). There were high rates of infection in all age groups, and the prevalence increased with age. However, multivariate logistic regression analysis showed that HSV-2 prevalence was not significantly associated with increasing age, sex, marital status, occupation, educational status, and number of sex partners (P > 0.05). Conclusions: The results highlight the potential public health impact of HSV-2 in Nigeria where anti-HSV-2 testing is not generally performed in all populations, especially considering the risk of neonatal transmission and the attendant complications at birth. https://jidc.org/index.php/journal/article/view/567Herpes Simplex Virus Type-2AntibodiesPatientsJos |
| spellingShingle | Yusuf A. Agabi Edmund B. Banwat John D Mawak Patricia M Lar Nanma Dashe Michael M Dashen Moses P Adoga Felicia Y Agabi Hashimu Zakari Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria Journal of Infection in Developing Countries Herpes Simplex Virus Type-2 Antibodies Patients Jos |
| title | Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria |
| title_full | Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria |
| title_fullStr | Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria |
| title_full_unstemmed | Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria |
| title_short | Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria |
| title_sort | seroprevalence of herpes simplex virus type 2 among patients attending the sexually transmitted infections clinic in jos nigeria |
| topic | Herpes Simplex Virus Type-2 Antibodies Patients Jos |
| url | https://jidc.org/index.php/journal/article/view/567 |
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