Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria

Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria

Background: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide.  There is little information on the prevalence of HSV-2 in Nigeria.        Methodology: Specimens were collected from 162 volu...

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Bibliographic Details
Main Authors: Yusuf A. Agabi, Edmund B. Banwat, John D Mawak, Patricia M Lar, Nanma Dashe, Michael M Dashen, Moses P Adoga, Felicia Y Agabi, Hashimu Zakari
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2010-05-01
Series:Journal of Infection in Developing Countries
Subjects:
Herpes Simplex Virus Type-2
Antibodies
Patients
Jos
Online Access:https://jidc.org/index.php/journal/article/view/567
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Summary:Background: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide.  There is little information on the prevalence of HSV-2 in Nigeria.        Methodology: Specimens were collected from 162 volunteers attending Jos University Teaching Hospital and tested for HSV-2 antibodies using HSV-2 Type specific IgG EIA test kit (Globalemed LLC Alexandria VA, USA). Data were analyzed using SPSS version 13.0. P values ≤ 0.05 were considered significant. numbr Results: Out of the 162 individuals tested, 141 (87.0%) were HSV-2 positive. Infected individuals were more likely to be male than female (92.8% versus 86.4%; P > 0.05). There were high rates of infection in all age groups, and the prevalence increased with age. However, multivariate logistic regression analysis showed that HSV-2 prevalence was not significantly associated with increasing age, sex, marital status, occupation, educational status, and number of sex partners (P > 0.05).   Conclusions: The results highlight the potential public health impact of HSV-2 in Nigeria where anti-HSV-2 testing is not generally performed in all populations, especially considering the risk of neonatal transmission and the attendant complications at birth.
ISSN:1972-2680

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