Complications with rotavirus: A single center experiences

Rotavirus is an important morbidity and mortality agent among previously healthy infants. Rotavirus gastroenteritis (RG) causes severe fluid and electrolyte imbalance and development of fatal complications during course of the disease, if untreated. Although there are few case reports in the...

Full description

Saved in:
Bibliographic Details
Main Authors: Bilge Aldemir-Kocabaş, Adem Karbuz, Halil Özdemir, Tuğçe Tural-Kara, Anıl Tapısız, Nurşen Belet, Haluk Güriz, Ergin Çiftçi, Erdal İnce
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2016-12-01
Series:The Turkish Journal of Pediatrics
Subjects:
Online Access:https://turkjpediatr.org/article/view/1168
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850024176066232320
author Bilge Aldemir-Kocabaş
Adem Karbuz
Halil Özdemir
Tuğçe Tural-Kara
Anıl Tapısız
Nurşen Belet
Haluk Güriz
Ergin Çiftçi
Erdal İnce
author_facet Bilge Aldemir-Kocabaş
Adem Karbuz
Halil Özdemir
Tuğçe Tural-Kara
Anıl Tapısız
Nurşen Belet
Haluk Güriz
Ergin Çiftçi
Erdal İnce
author_sort Bilge Aldemir-Kocabaş
collection DOAJ
description Rotavirus is an important morbidity and mortality agent among previously healthy infants. Rotavirus gastroenteritis (RG) causes severe fluid and electrolyte imbalance and development of fatal complications during course of the disease, if untreated. Although there are few case reports in the literature regarding septicemia after RG, it is one of the most important complications of the disease. The main reason of septicemia is unknown but it can be associated with severe consequences such as septic shock, endocarditis, and even death. If complications are taken into consideration on the course of disease, morbidity and mortality can be reduced. Herein, we evaluated the clinical characteristics, incidence and types of the complications during RG in this retrospective study. We evaluated a total of 276 patients (164 male, 112 female) diagnosed with RG between January 2006 and February 2013 at the department of Pediatric Infectious Disease. Male to female ratio was 1.5 and the median age at admission was 12 months (1-102 months). None of the patients had a history of Rotavirus immunization. While overall complication rate was 44.2%, the most common complication related RG was electrolyte imbalance and the second common complication was septicemia (32.6% and 6.5%, respectively). Klebsiella, E. coli and Candida species were the most common isolated microorganisms from the blood cultures. Rotavirus gastroenteritis is still an important cause of morbidity in children which can cause serious complications such as sepsis. Lack of rotavirus vaccine in our national immunization program might contribute to the related complications and prolonged hospitalization, health care expenses and family work loss, as well.
format Article
id doaj-art-0192648a1ecd45f4875f84eefbe0f707
institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 2016-12-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-0192648a1ecd45f4875f84eefbe0f7072025-08-20T03:01:11ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212016-12-0158610.24953/turkjped.2016.06.005Complications with rotavirus: A single center experiencesBilge Aldemir-Kocabaş0Adem Karbuz1Halil Özdemir2Tuğçe Tural-Kara3Anıl Tapısız4Nurşen Belet5Haluk Güriz6Ergin Çiftçi7Erdal İnce8Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.Department of Clinical Microbiology, Ankara University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey. Rotavirus is an important morbidity and mortality agent among previously healthy infants. Rotavirus gastroenteritis (RG) causes severe fluid and electrolyte imbalance and development of fatal complications during course of the disease, if untreated. Although there are few case reports in the literature regarding septicemia after RG, it is one of the most important complications of the disease. The main reason of septicemia is unknown but it can be associated with severe consequences such as septic shock, endocarditis, and even death. If complications are taken into consideration on the course of disease, morbidity and mortality can be reduced. Herein, we evaluated the clinical characteristics, incidence and types of the complications during RG in this retrospective study. We evaluated a total of 276 patients (164 male, 112 female) diagnosed with RG between January 2006 and February 2013 at the department of Pediatric Infectious Disease. Male to female ratio was 1.5 and the median age at admission was 12 months (1-102 months). None of the patients had a history of Rotavirus immunization. While overall complication rate was 44.2%, the most common complication related RG was electrolyte imbalance and the second common complication was septicemia (32.6% and 6.5%, respectively). Klebsiella, E. coli and Candida species were the most common isolated microorganisms from the blood cultures. Rotavirus gastroenteritis is still an important cause of morbidity in children which can cause serious complications such as sepsis. Lack of rotavirus vaccine in our national immunization program might contribute to the related complications and prolonged hospitalization, health care expenses and family work loss, as well. https://turkjpediatr.org/article/view/1168complicationsrotavirussepticemiavaccine
spellingShingle Bilge Aldemir-Kocabaş
Adem Karbuz
Halil Özdemir
Tuğçe Tural-Kara
Anıl Tapısız
Nurşen Belet
Haluk Güriz
Ergin Çiftçi
Erdal İnce
Complications with rotavirus: A single center experiences
The Turkish Journal of Pediatrics
complications
rotavirus
septicemia
vaccine
title Complications with rotavirus: A single center experiences
title_full Complications with rotavirus: A single center experiences
title_fullStr Complications with rotavirus: A single center experiences
title_full_unstemmed Complications with rotavirus: A single center experiences
title_short Complications with rotavirus: A single center experiences
title_sort complications with rotavirus a single center experiences
topic complications
rotavirus
septicemia
vaccine
url https://turkjpediatr.org/article/view/1168
work_keys_str_mv AT bilgealdemirkocabas complicationswithrotavirusasinglecenterexperiences
AT ademkarbuz complicationswithrotavirusasinglecenterexperiences
AT halilozdemir complicationswithrotavirusasinglecenterexperiences
AT tugceturalkara complicationswithrotavirusasinglecenterexperiences
AT anıltapısız complicationswithrotavirusasinglecenterexperiences
AT nursenbelet complicationswithrotavirusasinglecenterexperiences
AT halukguriz complicationswithrotavirusasinglecenterexperiences
AT erginciftci complicationswithrotavirusasinglecenterexperiences
AT erdalince complicationswithrotavirusasinglecenterexperiences