The divergent outcome of IL-4Rα signalling on Foxp3 T regulatory cells in listeriosis and tuberculosis

The divergent outcome of IL-4Rα signalling on Foxp3 T regulatory cells in listeriosis and tuberculosis

IntroductionForkhead box P3 (Foxp3) T regulatory cells are critical for maintaining self-tolerance, immune homeostasis, and regulating the immune system.MethodsWe investigated interleukin-4 receptor alpha (IL-4Rα) signalling on T regulatory cells (Tregs) during Listeria monocytogenes (L. monocytogen...

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Bibliographic Details
Main Authors: Julius E. Chia, Robert P. Rousseau, Mumin Ozturk, Sibongiseni K. L. Poswayo, Rodney Lucas, Frank Brombacher, Suraj P. Parihar
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
listeriosis
IL-4Rα
Foxp3 T cells
mice
tuberculosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427055/full
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