ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION

Objective: Ranson criteria, introduced in 1974, was the first clinical prediction rule for acute pancreatitis in which five admission parameters and six (or five) late components collected within 48 hours were used to reach a clinical decision. This 48- hour follow-up requirement was not convenient...

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Main Authors: Naci Şenkal, Latif Karahan, Ali Emre Bardak, Hilal Konyaoğlu, Ebru Teberik Kama, İsmail İnci, Leman Damla Ercan, Alpay Medetalibeyoğlu, Tufan Tükek
Format: Article
Language:English
Published: Istanbul University Press 2023-08-01
Series:İstanbul Tıp Fakültesi Dergisi
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Online Access:https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/1FC3C5CE63704D49A535A9773FD6411A
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author Naci Şenkal
Latif Karahan
Ali Emre Bardak
Hilal Konyaoğlu
Ebru Teberik Kama
İsmail İnci
Leman Damla Ercan
Alpay Medetalibeyoğlu
Tufan Tükek
author_facet Naci Şenkal
Latif Karahan
Ali Emre Bardak
Hilal Konyaoğlu
Ebru Teberik Kama
İsmail İnci
Leman Damla Ercan
Alpay Medetalibeyoğlu
Tufan Tükek
author_sort Naci Şenkal
collection DOAJ
description Objective: Ranson criteria, introduced in 1974, was the first clinical prediction rule for acute pancreatitis in which five admission parameters and six (or five) late components collected within 48 hours were used to reach a clinical decision. This 48- hour follow-up requirement was not convenient for use in the Emergency Department setting. This study was undertaken to assess whether five admission Ranson parameters may have use in differentiating edematous pancreatitis from necrotizing pancreatitis in the emergency department setting.Material and Method: Patient data for this retrospective cohortstudy was gathered from 205 patients treated for acute pancreatitis from January 2018 to December 2022 in a tertiarycare center. The patient files were extracted from the archives for clinical data gathering. Laboratory admission data and radiology reports were extracted from the automated laboratory reporting system.Result: The 205 acute pancreatitis patients were mostly female and in their sixth decade. The etiology was mostly biliary pancreatitis (76%). Patient history revealed that 80% was the first attack. The radiologic imaging study review revealed the majority of the patients had edematous pancreatitis (87%). Higher scores in admission Ranson score (aRS) weakly predicted increasingly higher probability (2.6% for aRS 0 to 28.6% for aRS 4-5) for the presence of necrosis without reaching statistical significance (p=0.055) When components of the score were analyzed, age, LDH levels, and glucose had no discriminating value, WBC parameter posi tivity significantly increased the odds of necrotizing pancreatitis,whereas positive AST level significantly decreased the risk of necrotizing pancreatitis.Conclusion: In conclusion, aRS had little utility in predicting pancreatic necrosis
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spelling doaj-art-0182ef9754994e9e8e1fd986bd53f1352025-08-20T02:57:26ZengIstanbul University Pressİstanbul Tıp Fakültesi Dergisi1305-64412023-08-0186319820310.26650/IUITFD.1272976123456ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSIONNaci Şenkal0https://orcid.org/0000-0001-7072-8724Latif Karahan1https://orcid.org/0000-0002-3465-1085Ali Emre Bardak2https://orcid.org/0000-0002-3073-8538Hilal Konyaoğlu3https://orcid.org/0000-0003-3036-9143Ebru Teberik Kama4https://orcid.org/0000-0003-3958-1642İsmail İnci5https://orcid.org/0009-0008-8593-9709Leman Damla Ercan6https://orcid.org/0000-0001-9637-571XAlpay Medetalibeyoğlu7https://orcid.org/0000-0002-5829-9186Tufan Tükek8https://orcid.org/0000-0002-4237-1163İstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, TürkiyeArnavutköy Devlet Hastanesi, istanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, TürkiyeObjective: Ranson criteria, introduced in 1974, was the first clinical prediction rule for acute pancreatitis in which five admission parameters and six (or five) late components collected within 48 hours were used to reach a clinical decision. This 48- hour follow-up requirement was not convenient for use in the Emergency Department setting. This study was undertaken to assess whether five admission Ranson parameters may have use in differentiating edematous pancreatitis from necrotizing pancreatitis in the emergency department setting.Material and Method: Patient data for this retrospective cohortstudy was gathered from 205 patients treated for acute pancreatitis from January 2018 to December 2022 in a tertiarycare center. The patient files were extracted from the archives for clinical data gathering. Laboratory admission data and radiology reports were extracted from the automated laboratory reporting system.Result: The 205 acute pancreatitis patients were mostly female and in their sixth decade. The etiology was mostly biliary pancreatitis (76%). Patient history revealed that 80% was the first attack. The radiologic imaging study review revealed the majority of the patients had edematous pancreatitis (87%). Higher scores in admission Ranson score (aRS) weakly predicted increasingly higher probability (2.6% for aRS 0 to 28.6% for aRS 4-5) for the presence of necrosis without reaching statistical significance (p=0.055) When components of the score were analyzed, age, LDH levels, and glucose had no discriminating value, WBC parameter posi tivity significantly increased the odds of necrotizing pancreatitis,whereas positive AST level significantly decreased the risk of necrotizing pancreatitis.Conclusion: In conclusion, aRS had little utility in predicting pancreatic necrosishttps://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/1FC3C5CE63704D49A535A9773FD6411Aranson scoreacute pancreatitisnecrotizing pancreatitisedematous pancreatitis
spellingShingle Naci Şenkal
Latif Karahan
Ali Emre Bardak
Hilal Konyaoğlu
Ebru Teberik Kama
İsmail İnci
Leman Damla Ercan
Alpay Medetalibeyoğlu
Tufan Tükek
ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION
İstanbul Tıp Fakültesi Dergisi
ranson score
acute pancreatitis
necrotizing pancreatitis
edematous pancreatitis
title ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION
title_full ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION
title_fullStr ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION
title_full_unstemmed ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION
title_short ASSESSMENT OF THE RANSON SCORE IN ACUTE PANCREATITIS: ITS VALUE IN AN EMERGENCY SETTING UPON ADMISSION
title_sort assessment of the ranson score in acute pancreatitis its value in an emergency setting upon admission
topic ranson score
acute pancreatitis
necrotizing pancreatitis
edematous pancreatitis
url https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/1FC3C5CE63704D49A535A9773FD6411A
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