Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics

Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics

The aging of pancreatic beta cells is closely associated with various diseases, such as impaired glucose tolerance, yet the underlying regulatory mechanisms remain unclear. In this study, we screened young and aged mouse pancreatic beta cells' high-throughput sequencing data from the GEO public...

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Bibliographic Details
Main Authors: Junqi Yang, Yumin Ma, Jiang Liu, Qingtian Zhu, Rui Zhou, Chenchen Yuan, Yanbing Ding, Weiming Xiao, Weijuan Gong, Qing Shan, Guotao Lu, Hongwei Xu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Experimental Gerontology
Subjects:
Bioinformatics
Aging
Pancreatic beta cells
YY1
P38/JNK MAPK
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556524002791
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