Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study
Objective To assess the effect of aerobic exercise on the cognition and functional capacity in Alzheimer’s disease (AD) patients. Method Elderly (n=20) with mild dementia (NINCDS-ADRDA/CDR1) were randomly assigned to an exercise group (EG) on a treadmill (30 minutes, twice a week and moderate inte...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
2014-03-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000300190&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850231861920399360 |
|---|---|
| author | Cynthia Arcoverde Andrea Deslandes Helena Moraes Cloyra Almeida Narahyana Bom de Araujo Paulo Eduardo Vasques Heitor Silveira Jerson Laks |
| author_facet | Cynthia Arcoverde Andrea Deslandes Helena Moraes Cloyra Almeida Narahyana Bom de Araujo Paulo Eduardo Vasques Heitor Silveira Jerson Laks |
| author_sort | Cynthia Arcoverde |
| collection | DOAJ |
| description | Objective To assess the effect of aerobic exercise on the cognition and functional capacity in Alzheimer’s disease (AD) patients. Method Elderly (n=20) with mild dementia (NINCDS-ADRDA/CDR1) were randomly assigned to an exercise group (EG) on a treadmill (30 minutes, twice a week and moderate intensity of 60% VO2max) and control group (GC) 10 patients. The primary outcome measure was the cognitive function using Cambridge Cognitive Examination (CAMCOG). Specifics instruments were also applied to evaluate executive function, memory, attention and concentration, cognitive flexibility, inhibitory control and functional capacity. Results After 16 weeks, the EG showed improvement in cognition CAMCOG whereas the CG declined. Compared to the CG, the EG presented significant improvement on the functional capacity. The analysis of the effect size has shown a favorable response to the physical exercise in all dependent variables. Conclusion Walking on treadmill may be recommended as an augmentation treatment for patients with AD. |
| format | Article |
| id | doaj-art-017e69dc245f4947845daf1e86308dbe |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2014-03-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-017e69dc245f4947845daf1e86308dbe2025-08-20T02:03:24ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272014-03-0172319019610.1590/0004-282X20130231S0004-282X2014000300190Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled studyCynthia ArcoverdeAndrea DeslandesHelena MoraesCloyra AlmeidaNarahyana Bom de AraujoPaulo Eduardo VasquesHeitor SilveiraJerson LaksObjective To assess the effect of aerobic exercise on the cognition and functional capacity in Alzheimer’s disease (AD) patients. Method Elderly (n=20) with mild dementia (NINCDS-ADRDA/CDR1) were randomly assigned to an exercise group (EG) on a treadmill (30 minutes, twice a week and moderate intensity of 60% VO2max) and control group (GC) 10 patients. The primary outcome measure was the cognitive function using Cambridge Cognitive Examination (CAMCOG). Specifics instruments were also applied to evaluate executive function, memory, attention and concentration, cognitive flexibility, inhibitory control and functional capacity. Results After 16 weeks, the EG showed improvement in cognition CAMCOG whereas the CG declined. Compared to the CG, the EG presented significant improvement on the functional capacity. The analysis of the effect size has shown a favorable response to the physical exercise in all dependent variables. Conclusion Walking on treadmill may be recommended as an augmentation treatment for patients with AD.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000300190&lng=en&tlng=endoença de Alzheimerexercício aeróbiotreinamento físicofunção cognitivacapacidade funcional |
| spellingShingle | Cynthia Arcoverde Andrea Deslandes Helena Moraes Cloyra Almeida Narahyana Bom de Araujo Paulo Eduardo Vasques Heitor Silveira Jerson Laks Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study Arquivos de Neuro-Psiquiatria doença de Alzheimer exercício aeróbio treinamento físico função cognitiva capacidade funcional |
| title | Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
| title_full | Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
| title_fullStr | Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
| title_full_unstemmed | Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
| title_short | Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
| title_sort | treadmill training as an augmentation treatment for alzheimer s disease a pilot randomized controlled study |
| topic | doença de Alzheimer exercício aeróbio treinamento físico função cognitiva capacidade funcional |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000300190&lng=en&tlng=en |
| work_keys_str_mv | AT cynthiaarcoverde treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy AT andreadeslandes treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy AT helenamoraes treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy AT cloyraalmeida treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy AT narahyanabomdearaujo treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy AT pauloeduardovasques treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy AT heitorsilveira treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy AT jersonlaks treadmilltrainingasanaugmentationtreatmentforalzheimersdiseaseapilotrandomizedcontrolledstudy |