Sarcoidosis Presenting as Löfgren’s Syndrome with Myopathy
A 34-year-old female patient, who had proximal muscle weakness for 8 months, presented with erythema nodosum lesions on the pretibial region in addition to pain, swelling, and movement restriction in both ankles for the last one month. Thoracic CT demonstrated hilar and mediastinal lymphadenopathy....
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2013/125251 |
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| _version_ | 1849305524790624256 |
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| author | Şenol Kobak Murat Yalçin Fidan Sever Guray Oncel |
| author_facet | Şenol Kobak Murat Yalçin Fidan Sever Guray Oncel |
| author_sort | Şenol Kobak |
| collection | DOAJ |
| description | A 34-year-old female patient, who had proximal muscle weakness for 8 months, presented with erythema nodosum lesions on the pretibial region in addition to pain, swelling, and movement restriction in both ankles for the last one month. Thoracic CT demonstrated hilar and mediastinal lymphadenopathy. She underwent mediastinoscopic lymph node biopsy; biopsy result was consistent with noncaseating granuloma. Serum angiotensin converting enzyme level and muscle enzymes have been elevated. Muscular MRI and EMG findings were consistent with myositis. Muscle biopsy was done, and myopathy was found. The patient was diagnosed with sarcoidosis, Löfgren's syndrome, and sarcoid myopathy. The patient displayed remarkable clinical and radiological regression after 6-month corticosteroid and MTX therapy. |
| format | Article |
| id | doaj-art-017ce87558ab43109da5d8d53545bc23 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-017ce87558ab43109da5d8d53545bc232025-08-20T03:55:24ZengWileyCase Reports in Rheumatology2090-68892090-68972013-01-01201310.1155/2013/125251125251Sarcoidosis Presenting as Löfgren’s Syndrome with MyopathyŞenol Kobak0Murat Yalçin1Fidan Sever2Guray Oncel3Department of Rheumatology, Şifa University Faculty of Medicine, Bornova, 35100 Izmir, TurkeyDepartment of Rheumatology, Şifa University Faculty of Medicine, Bornova, 35100 Izmir, TurkeyDepartment of Chest Diseases, Şifa University Faculty of Medicine, Izmir, TurkeyDepartment of Radiology, Şifa University Faculty of Medicine, Izmir, TurkeyA 34-year-old female patient, who had proximal muscle weakness for 8 months, presented with erythema nodosum lesions on the pretibial region in addition to pain, swelling, and movement restriction in both ankles for the last one month. Thoracic CT demonstrated hilar and mediastinal lymphadenopathy. She underwent mediastinoscopic lymph node biopsy; biopsy result was consistent with noncaseating granuloma. Serum angiotensin converting enzyme level and muscle enzymes have been elevated. Muscular MRI and EMG findings were consistent with myositis. Muscle biopsy was done, and myopathy was found. The patient was diagnosed with sarcoidosis, Löfgren's syndrome, and sarcoid myopathy. The patient displayed remarkable clinical and radiological regression after 6-month corticosteroid and MTX therapy.http://dx.doi.org/10.1155/2013/125251 |
| spellingShingle | Şenol Kobak Murat Yalçin Fidan Sever Guray Oncel Sarcoidosis Presenting as Löfgren’s Syndrome with Myopathy Case Reports in Rheumatology |
| title | Sarcoidosis Presenting as Löfgren’s Syndrome with Myopathy |
| title_full | Sarcoidosis Presenting as Löfgren’s Syndrome with Myopathy |
| title_fullStr | Sarcoidosis Presenting as Löfgren’s Syndrome with Myopathy |
| title_full_unstemmed | Sarcoidosis Presenting as Löfgren’s Syndrome with Myopathy |
| title_short | Sarcoidosis Presenting as Löfgren’s Syndrome with Myopathy |
| title_sort | sarcoidosis presenting as lofgren s syndrome with myopathy |
| url | http://dx.doi.org/10.1155/2013/125251 |
| work_keys_str_mv | AT senolkobak sarcoidosispresentingaslofgrenssyndromewithmyopathy AT muratyalcin sarcoidosispresentingaslofgrenssyndromewithmyopathy AT fidansever sarcoidosispresentingaslofgrenssyndromewithmyopathy AT gurayoncel sarcoidosispresentingaslofgrenssyndromewithmyopathy |