Lipid peroxidation, antioxidant protection, and rheology disturbances in coronary heart disease pathogenesis
In 126 patients with coronary heart disease (CHD), complex assessment of lipid peroxidation (LP) and antioxidant protection, blood rheology, and their interaction with clinical and hemodynamical parameters, was performed. According to correlation analysis, CHD patients demonstrated associations betw...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2006-04-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1815 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | In 126 patients with coronary heart disease (CHD), complex assessment of lipid peroxidation (LP) and antioxidant protection, blood rheology, and their interaction with clinical and hemodynamical parameters, was performed. According to correlation analysis, CHD patients demonstrated associations between LP parameters, antioxidant enzyme levels and antioxidants of plasma anti-radical pool. PL parameters correlated with red blood cell and platelet functional activity. Regulatory role of antioxidant system (AOS) in lipid peroxidation metabolism and peroxide blood cell damage in CHD was demonstrated. Associations between PL, AOS, and hemorheology parameters were detected, confirming pathogenetic role of these disturbances in CHD pathogenesis. |
|---|---|
| ISSN: | 1560-4071 2618-7620 |