Childhood Obesity and Obstructive Sleep Apnea
The global epidemic of childhood and adolescent obesity and its immediate as well as long-term consequences for obese individuals and society as a whole cannot be overemphasized. Obesity in childhood and adolescence is associated with an increased risk of adult obesity and clinically significant con...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2012/134202 |
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| _version_ | 1849305518055620608 |
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| author | Indra Narang Joseph L. Mathew |
| author_facet | Indra Narang Joseph L. Mathew |
| author_sort | Indra Narang |
| collection | DOAJ |
| description | The global epidemic of childhood and adolescent obesity and its immediate as well as long-term consequences for obese individuals and society as a whole cannot be overemphasized. Obesity in childhood and adolescence is associated with an increased risk of adult obesity and clinically significant consequences affecting the cardiovascular and metabolic systems. Importantly, obesity is additionally complicated by obstructive sleep apnea (OSA), occurring in up to 60% of obese children. OSA, which is diagnosed using the gold standard polysomnogram (PSG), is characterised by snoring, recurrent partial (hypopneas) or complete (apneas) obstruction of the upper airway. OSA is frequently associated with intermittent oxyhemoglobin desaturations, sleep disruption, and sleep fragmentation. There is emerging data that OSA is associated with cardiovascular burden including systemic hypertension, changes in ventricular structure and function, arterial stiffness, and metabolic syndromes. Thus, OSA in the context of obesity may independently or synergistically magnify the underlying cardiovascular and metabolic burden. This is of importance as early recognition and treatment of OSA in obese children are likely to result in the reduction of cardiometabolic burden in obese children. This paper summarizes the current state of understanding of obesity-related OSA. Specifically, this paper will discuss epidemiology, pathophysiology, cardiometabolic burden, and management of obese children and adolescents with OSA. |
| format | Article |
| id | doaj-art-0168a91e478b4470b299cb1aba60d3e3 |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-0168a91e478b4470b299cb1aba60d3e32025-08-20T03:55:24ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322012-01-01201210.1155/2012/134202134202Childhood Obesity and Obstructive Sleep ApneaIndra Narang0Joseph L. Mathew1Division of Respiratory Medicine, The Hospital For Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, CanadaDivision of Respiratory Medicine, The Hospital For Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, CanadaThe global epidemic of childhood and adolescent obesity and its immediate as well as long-term consequences for obese individuals and society as a whole cannot be overemphasized. Obesity in childhood and adolescence is associated with an increased risk of adult obesity and clinically significant consequences affecting the cardiovascular and metabolic systems. Importantly, obesity is additionally complicated by obstructive sleep apnea (OSA), occurring in up to 60% of obese children. OSA, which is diagnosed using the gold standard polysomnogram (PSG), is characterised by snoring, recurrent partial (hypopneas) or complete (apneas) obstruction of the upper airway. OSA is frequently associated with intermittent oxyhemoglobin desaturations, sleep disruption, and sleep fragmentation. There is emerging data that OSA is associated with cardiovascular burden including systemic hypertension, changes in ventricular structure and function, arterial stiffness, and metabolic syndromes. Thus, OSA in the context of obesity may independently or synergistically magnify the underlying cardiovascular and metabolic burden. This is of importance as early recognition and treatment of OSA in obese children are likely to result in the reduction of cardiometabolic burden in obese children. This paper summarizes the current state of understanding of obesity-related OSA. Specifically, this paper will discuss epidemiology, pathophysiology, cardiometabolic burden, and management of obese children and adolescents with OSA.http://dx.doi.org/10.1155/2012/134202 |
| spellingShingle | Indra Narang Joseph L. Mathew Childhood Obesity and Obstructive Sleep Apnea Journal of Nutrition and Metabolism |
| title | Childhood Obesity and Obstructive Sleep Apnea |
| title_full | Childhood Obesity and Obstructive Sleep Apnea |
| title_fullStr | Childhood Obesity and Obstructive Sleep Apnea |
| title_full_unstemmed | Childhood Obesity and Obstructive Sleep Apnea |
| title_short | Childhood Obesity and Obstructive Sleep Apnea |
| title_sort | childhood obesity and obstructive sleep apnea |
| url | http://dx.doi.org/10.1155/2012/134202 |
| work_keys_str_mv | AT indranarang childhoodobesityandobstructivesleepapnea AT josephlmathew childhoodobesityandobstructivesleepapnea |