The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study
Aim. Investigate the disruption of geniculocalcarine tract (GCT) in different occipital neoplasm by diffusion tensor imaging (DTI). Methods. Thirty-two subjects (44.1 ± 3.6 years) who had single occipital neoplasm (9 gliomas, 6 meningiomas, and 17 metastatic tumors) with ipsilateral GCT involved and...
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Wiley
2016-01-01
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| Series: | Radiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/8213076 |
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| author | Yan Zhang Sihai Wan Ge Wen Xuelin Zhang |
| author_facet | Yan Zhang Sihai Wan Ge Wen Xuelin Zhang |
| author_sort | Yan Zhang |
| collection | DOAJ |
| description | Aim. Investigate the disruption of geniculocalcarine tract (GCT) in different occipital neoplasm by diffusion tensor imaging (DTI). Methods. Thirty-two subjects (44.1 ± 3.6 years) who had single occipital neoplasm (9 gliomas, 6 meningiomas, and 17 metastatic tumors) with ipsilateral GCT involved and thirty healthy subjects (39.2 ± 3.3 years) underwent conventional sequences scanning and diffusion tensor imaging by a 1.5T MR scanner. The diffusion-sensitive gradient direction is 13. Compare the fractional anisotropy (FA) and mean diffusivity (MD) values of healthy GCT with the corresponding values of GCT in peritumoral edema area. Perform diffusion tensor tractography (DTT) on GCT by the line propagation technique in all subjects. Results. The FA values of GCT in peritumoral edema area decreased (P=0.001) while the MD values increased (P=0.002) when compared with healthy subjects. There was no difference in the FA values across tumor types (P=0.114) while the MD values of GCT in the metastatic tumor group were higher than the other groups (P=0.001). GCTs were infiltrated in all the 9 gliomas cases, with displacement in 2 cases and disruption in 7 cases. GCTs were displaced in 6 meningiomas cases. GCTs were displaced in all the 7 metastatic cases, with disruption in 7 cases. Conclusions. DTI represents valid markers for evaluating GCT’s disruption in occipital neoplasm. The disruption of GCT varies according to the properties of neoplasm. |
| format | Article |
| id | doaj-art-015a8687e68b4f0f8bbdc0d78327002e |
| institution | Kabale University |
| issn | 2090-1941 2090-195X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
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| series | Radiology Research and Practice |
| spelling | doaj-art-015a8687e68b4f0f8bbdc0d78327002e2025-08-20T03:55:27ZengWileyRadiology Research and Practice2090-19412090-195X2016-01-01201610.1155/2016/82130768213076The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging StudyYan Zhang0Sihai Wan1Ge Wen2Xuelin Zhang3Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, Guangdong 510060, ChinaDepartment of Radiology, Lu Shan Sanatorium, Nanjing Military Region, Jiujiang, Jiangxi 332000, ChinaDepartment of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, ChinaDepartment of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, ChinaAim. Investigate the disruption of geniculocalcarine tract (GCT) in different occipital neoplasm by diffusion tensor imaging (DTI). Methods. Thirty-two subjects (44.1 ± 3.6 years) who had single occipital neoplasm (9 gliomas, 6 meningiomas, and 17 metastatic tumors) with ipsilateral GCT involved and thirty healthy subjects (39.2 ± 3.3 years) underwent conventional sequences scanning and diffusion tensor imaging by a 1.5T MR scanner. The diffusion-sensitive gradient direction is 13. Compare the fractional anisotropy (FA) and mean diffusivity (MD) values of healthy GCT with the corresponding values of GCT in peritumoral edema area. Perform diffusion tensor tractography (DTT) on GCT by the line propagation technique in all subjects. Results. The FA values of GCT in peritumoral edema area decreased (P=0.001) while the MD values increased (P=0.002) when compared with healthy subjects. There was no difference in the FA values across tumor types (P=0.114) while the MD values of GCT in the metastatic tumor group were higher than the other groups (P=0.001). GCTs were infiltrated in all the 9 gliomas cases, with displacement in 2 cases and disruption in 7 cases. GCTs were displaced in 6 meningiomas cases. GCTs were displaced in all the 7 metastatic cases, with disruption in 7 cases. Conclusions. DTI represents valid markers for evaluating GCT’s disruption in occipital neoplasm. The disruption of GCT varies according to the properties of neoplasm.http://dx.doi.org/10.1155/2016/8213076 |
| spellingShingle | Yan Zhang Sihai Wan Ge Wen Xuelin Zhang The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study Radiology Research and Practice |
| title | The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study |
| title_full | The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study |
| title_fullStr | The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study |
| title_full_unstemmed | The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study |
| title_short | The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study |
| title_sort | disruption of geniculocalcarine tract in occipital neoplasm a diffusion tensor imaging study |
| url | http://dx.doi.org/10.1155/2016/8213076 |
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