Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitioners

Context: Owing to the increasing number of cancer cases, and introduction of newer drugs like bisphosphonates (BP) for the management of metastatic bone disease, complications such as bisphosphonate-related osteonecrosis of the jaw (BRONJ) have come into light. However, several of the treating physi...

Full description

Saved in:
Bibliographic Details
Main Authors: Shalini Krishnan, Vijith Shetty, Jayarama Shetty, Gogineni Subhas Babu, T P Rajeev
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2019-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=2;spage=257;epage=264;aulast=Krishnan
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850246566913245184
author Shalini Krishnan
Vijith Shetty
Jayarama Shetty
Gogineni Subhas Babu
T P Rajeev
author_facet Shalini Krishnan
Vijith Shetty
Jayarama Shetty
Gogineni Subhas Babu
T P Rajeev
author_sort Shalini Krishnan
collection DOAJ
description Context: Owing to the increasing number of cancer cases, and introduction of newer drugs like bisphosphonates (BP) for the management of metastatic bone disease, complications such as bisphosphonate-related osteonecrosis of the jaw (BRONJ) have come into light. However, several of the treating physicians are not fully aware of this adverse effect. Aim: This study aimed to assess the knowledge and awareness of physicians regarding BRONJ and practices related to bisphosphonate use. Settings and Design: A cross-sectional study conducted among health-care professionals in various medical institutions in Mangalore. Subjects and Methods: A questionnaire was developed to assess the knowledge and awareness of physicians about osteonecrosis of the jaw and practices related to bisphosphonate use, consisting of 21 questions, 12 – knowledge based and 9 – practice based. The questionnaire was validated and distributed among 113 doctors; their responses assigned scores, tabulated and assessed. Statistical Analysis: One-way analysis of variance and Tukey test. Results: More than 50% of the medical professionals had a score <40%, which shows a lack of knowledge about BP and BRONJ. About 45% of the medical professionals in the study group failed to identify the clinical features of BRONJ, and 67.26% were unaware of the risk associated with tooth extractions and oral surgical procedures in the development of the condition. Conclusion: Bisphosphonate-related osteonecrosis is almost exclusively seen in the jaws and hence, the diagnosis usually made by a dental practitioner. Lack of awareness of jaw osteonecrosis among the medical practitioners can result in delay in providing the right treatment.
format Article
id doaj-art-01564caa889e4659bb78cd08b7a75db7
institution OA Journals
issn 0971-5851
0975-2129
language English
publishDate 2019-01-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-01564caa889e4659bb78cd08b7a75db72025-08-20T01:59:09ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292019-01-0140225726410.4103/ijmpo.ijmpo_20_18Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitionersShalini KrishnanVijith ShettyJayarama ShettyGogineni Subhas BabuT P RajeevContext: Owing to the increasing number of cancer cases, and introduction of newer drugs like bisphosphonates (BP) for the management of metastatic bone disease, complications such as bisphosphonate-related osteonecrosis of the jaw (BRONJ) have come into light. However, several of the treating physicians are not fully aware of this adverse effect. Aim: This study aimed to assess the knowledge and awareness of physicians regarding BRONJ and practices related to bisphosphonate use. Settings and Design: A cross-sectional study conducted among health-care professionals in various medical institutions in Mangalore. Subjects and Methods: A questionnaire was developed to assess the knowledge and awareness of physicians about osteonecrosis of the jaw and practices related to bisphosphonate use, consisting of 21 questions, 12 – knowledge based and 9 – practice based. The questionnaire was validated and distributed among 113 doctors; their responses assigned scores, tabulated and assessed. Statistical Analysis: One-way analysis of variance and Tukey test. Results: More than 50% of the medical professionals had a score <40%, which shows a lack of knowledge about BP and BRONJ. About 45% of the medical professionals in the study group failed to identify the clinical features of BRONJ, and 67.26% were unaware of the risk associated with tooth extractions and oral surgical procedures in the development of the condition. Conclusion: Bisphosphonate-related osteonecrosis is almost exclusively seen in the jaws and hence, the diagnosis usually made by a dental practitioner. Lack of awareness of jaw osteonecrosis among the medical practitioners can result in delay in providing the right treatment.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=2;spage=257;epage=264;aulast=Krishnanawarenessbisphosphonate-related osteonecrosis of the jawbisphosphonatesosteonecrosisphysicians
spellingShingle Shalini Krishnan
Vijith Shetty
Jayarama Shetty
Gogineni Subhas Babu
T P Rajeev
Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitioners
Indian Journal of Medical and Paediatric Oncology
awareness
bisphosphonate-related osteonecrosis of the jaw
bisphosphonates
osteonecrosis
physicians
title Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitioners
title_full Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitioners
title_fullStr Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitioners
title_full_unstemmed Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitioners
title_short Bisphosphonate-related osteonecrosis of the jaw: An enigma among medical practitioners
title_sort bisphosphonate related osteonecrosis of the jaw an enigma among medical practitioners
topic awareness
bisphosphonate-related osteonecrosis of the jaw
bisphosphonates
osteonecrosis
physicians
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=2;spage=257;epage=264;aulast=Krishnan
work_keys_str_mv AT shalinikrishnan bisphosphonaterelatedosteonecrosisofthejawanenigmaamongmedicalpractitioners
AT vijithshetty bisphosphonaterelatedosteonecrosisofthejawanenigmaamongmedicalpractitioners
AT jayaramashetty bisphosphonaterelatedosteonecrosisofthejawanenigmaamongmedicalpractitioners
AT goginenisubhasbabu bisphosphonaterelatedosteonecrosisofthejawanenigmaamongmedicalpractitioners
AT tprajeev bisphosphonaterelatedosteonecrosisofthejawanenigmaamongmedicalpractitioners