Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity

Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity

IntroductionEvidence of the benefits of cordycepin (Cpn) for treating obesity is accumulating, but detailed knowledge of its therapeutic targets and mechanisms remains limited. This study aimed to systematically identify Cpn’s therapeutic targets and pathways in Western diet (WD)-induced obesity usi...

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Bibliographic Details
Main Authors: Yu Liao, Mingchao Wang, Fuli Qin, Taotao Liu, Jiemei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
cordycepin
obesity
network pharmacology
quantitative transcriptomics
molecular docking
experimental validation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1571480/full
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