Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway

Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway

Abstract As one of the essential lignan derivative found in traditional Chinese medicinal herbs, secoisolariciresinol diglucoside (SDG) was proved to promote women’s health through its phytoestrogenic properties. Increasingly studies indicated that this compound could be a potential drug capable of...

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Main Authors: Yiqing Zhang, Xialu Liu, Zitong Zheng, Haiqiang Huang, Yurou Wang, Shuqin Wu, Yuan Shu, Yuxin Yang, Yufei Zhong, Pengfei Liao, Yongsong Wang, Zezheng Pan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Secoisolariciresinol diglucoside
Premature ovarian insufficiency
Granulosa cells
PI3K/Akt pathway
Network pharmacology
Online Access:https://doi.org/10.1038/s41598-024-83484-3
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https://doi.org/10.1038/s41598-024-83484-3

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