Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine

A Cu(II) complex [Cu(bipy)(H2O)2(SO4)]n (bipy = 2,2′-bipyridine) was synthesized by hydrothermal method and characterized structurally by elemental analyses, single crystal X-ray diffraction, infrared spectra, and thermogravimetry and differential scanning calorimetry. The Cu(II) was hexacoordinated...

Full description

Saved in:
Bibliographic Details
Main Authors: Ting Liu, Yi-An Wang, Qing Zang, Guo-Qing Zhong
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2018/8459638
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849686831631695872
author Ting Liu
Yi-An Wang
Qing Zang
Guo-Qing Zhong
author_facet Ting Liu
Yi-An Wang
Qing Zang
Guo-Qing Zhong
author_sort Ting Liu
collection DOAJ
description A Cu(II) complex [Cu(bipy)(H2O)2(SO4)]n (bipy = 2,2′-bipyridine) was synthesized by hydrothermal method and characterized structurally by elemental analyses, single crystal X-ray diffraction, infrared spectra, and thermogravimetry and differential scanning calorimetry. The Cu(II) was hexacoordinated by two N atoms from bipy, two O atoms from different sulfate radical anions, and two O atoms from two water molecules, forming a slightly distorted octahedral geometry, and bridged by sulfato groups into polymeric chains. Under the condition of physiological pH, the interaction mechanism between the complex and hsDNA was explored with acridine orange as a fluorescence probe by spectroscopic methods. The binding modes between the complex and hsDNA were the electrostatic and embedded modes.
format Article
id doaj-art-012014cc35504aebbd22fbb1f4e9df62
institution DOAJ
issn 1565-3633
1687-479X
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Bioinorganic Chemistry and Applications
spelling doaj-art-012014cc35504aebbd22fbb1f4e9df622025-08-20T03:22:33ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2018-01-01201810.1155/2018/84596388459638Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-BipyridineTing Liu0Yi-An Wang1Qing Zang2Guo-Qing Zhong3School of Material Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaSchool of Material Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaSchool of Material Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaSchool of Material Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaA Cu(II) complex [Cu(bipy)(H2O)2(SO4)]n (bipy = 2,2′-bipyridine) was synthesized by hydrothermal method and characterized structurally by elemental analyses, single crystal X-ray diffraction, infrared spectra, and thermogravimetry and differential scanning calorimetry. The Cu(II) was hexacoordinated by two N atoms from bipy, two O atoms from different sulfate radical anions, and two O atoms from two water molecules, forming a slightly distorted octahedral geometry, and bridged by sulfato groups into polymeric chains. Under the condition of physiological pH, the interaction mechanism between the complex and hsDNA was explored with acridine orange as a fluorescence probe by spectroscopic methods. The binding modes between the complex and hsDNA were the electrostatic and embedded modes.http://dx.doi.org/10.1155/2018/8459638
spellingShingle Ting Liu
Yi-An Wang
Qing Zang
Guo-Qing Zhong
Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine
Bioinorganic Chemistry and Applications
title Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine
title_full Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine
title_fullStr Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine
title_full_unstemmed Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine
title_short Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine
title_sort hydrothermal synthesis structural characterization and interaction mechanism with dna of copper ii complex containing 2 2 bipyridine
url http://dx.doi.org/10.1155/2018/8459638
work_keys_str_mv AT tingliu hydrothermalsynthesisstructuralcharacterizationandinteractionmechanismwithdnaofcopperiicomplexcontaining22bipyridine
AT yianwang hydrothermalsynthesisstructuralcharacterizationandinteractionmechanismwithdnaofcopperiicomplexcontaining22bipyridine
AT qingzang hydrothermalsynthesisstructuralcharacterizationandinteractionmechanismwithdnaofcopperiicomplexcontaining22bipyridine
AT guoqingzhong hydrothermalsynthesisstructuralcharacterizationandinteractionmechanismwithdnaofcopperiicomplexcontaining22bipyridine