Species Differences in Ezetimibe Glucuronidation

Background: Peclinical and clinical studies have revealed that ezetimibe, an approved cholesterol-absorption inhibitor, is rapidly and extensively metabolized to a more potent metabolite, ezetimibe glucuronide. Since different species are commonly used in the pharmacokinetic and pharmacodynamic stud...

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Bibliographic Details
Main Authors: Shalom Emmanuel, Eric A. Asare, Ting Du, Huan Xie, Dong Liang, Song Gao
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/14/11/569
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