Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway

Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway

Intervertebral disc degeneration (IDD) is a degenerative disease that is characterized by decreased matrix synthesis and extra degradation, nucleus pulposus cells (NPCs) apoptosis, and infiltration of inflammatory factors. Aloin, a colored compound from aloe plants, has been shown to be effective ag...

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Bibliographic Details
Main Authors:	Taiqiu Chen, Pengfei Li, Jincheng Qiu, Wenjun Hu, Shaoguang Li, Huihong Shi, Xianjian Qiu, Dongsheng Huang, Wenjie Gao, Anjing Liang
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2022/5865011
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