Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency

Succinylcholine is a commonly used medication in all aspects of anesthetic care, and there are a number of known side effects and complications associated with its use. However, when succinylcholine is used emergently, anesthesia providers must remain vigilant to undiagnosed conditions that pose add...

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Main Authors: Danny D. Bui, Shyamal R. Asher
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2020/8874617
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author Danny D. Bui
Shyamal R. Asher
author_facet Danny D. Bui
Shyamal R. Asher
author_sort Danny D. Bui
collection DOAJ
description Succinylcholine is a commonly used medication in all aspects of anesthetic care, and there are a number of known side effects and complications associated with its use. However, when succinylcholine is used emergently, anesthesia providers must remain vigilant to undiagnosed conditions that pose additional risks to patients. We report the use of succinylcholine to treat acute, refractory laryngospasm after extubation leading to prolonged neuromuscular paralysis. There are unique challenges presented by this case including the risk of anesthesia awareness with recall due to the cognitive biases that prevent the clinical diagnosis of pseudocholinesterase deficiency.
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spelling doaj-art-01145645ba6d4212984616bd09ce2e572025-08-20T03:22:31ZengWileyCase Reports in Anesthesiology2090-63822090-63902020-01-01202010.1155/2020/88746178874617Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase DeficiencyDanny D. Bui0Shyamal R. Asher1Rhode Island Hospital, Department of Anesthesiology, The Warren Alpert Medical School of Brown University, 593 Eddy St Davol 129, Providence, RI 02903, USARhode Island Hospital, Department of Anesthesiology, The Warren Alpert Medical School of Brown University, 593 Eddy St Davol 129, Providence, RI 02903, USASuccinylcholine is a commonly used medication in all aspects of anesthetic care, and there are a number of known side effects and complications associated with its use. However, when succinylcholine is used emergently, anesthesia providers must remain vigilant to undiagnosed conditions that pose additional risks to patients. We report the use of succinylcholine to treat acute, refractory laryngospasm after extubation leading to prolonged neuromuscular paralysis. There are unique challenges presented by this case including the risk of anesthesia awareness with recall due to the cognitive biases that prevent the clinical diagnosis of pseudocholinesterase deficiency.http://dx.doi.org/10.1155/2020/8874617
spellingShingle Danny D. Bui
Shyamal R. Asher
Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency
Case Reports in Anesthesiology
title Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency
title_full Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency
title_fullStr Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency
title_full_unstemmed Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency
title_short Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency
title_sort break the spasm with succinylcholine but risk intraoperative awareness with undiagnosed pseudocholinesterase deficiency
url http://dx.doi.org/10.1155/2020/8874617
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AT shyamalrasher breakthespasmwithsuccinylcholinebutriskintraoperativeawarenesswithundiagnosedpseudocholinesterasedeficiency