ACE2 and TMPRSS2 genetic polymorphisms as potential predictors of COVID−19 severity and outcome in females

ACE2 and TMPRSS2 genetic polymorphisms as potential predictors of COVID−19 severity and outcome in females

IntroductionACE2 and TMPRSS2 represent the major gateways for SARS-CoV-2 cell entry. The presence of functional ACE2 and TMPRSS2 genetic polymorphisms that affect gene expression may affect the risk of severe form of COVID-19 and its fatal outcome.Material and patientsThis observational study enroll...

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Main Authors: Sanja Matic, Dragan Milovanovic, Zeljko Mijailovic, Predrag Djurdjevic, Srdjan Stefanovic, Danijela Todorovic, Katarina Vitosevic, Vanja Canovic, Suzana Popovic, Nevena Milivojevic Dimitrijevic, Marko Zivanovic, Dragana Seklic, Sanja Aleksic, Nemanja Djordjevic, Milena Vukic, Nenad Vukovic, Nenad Filipovic, Dejan Baskic, Natasa Djordjevic
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Medicine
Subjects:
ACE2
TMPRSS2
COVID-19
severity
outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1493815/full
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