Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India

Abstract Background Tuberculosis (TB) poses a significant social and economic burden to households of persons with TB (PwTB). Despite free diagnosis and care under the National TB Elimination Programme (NTEP), individuals often experience significant out-of-pocket expenditure and lost productivity,...

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Main Authors: Kathiresan Jeyashree, Jeromie W. V. Thangaraj, Devika Shanmugasundaram, Sri Lakshmi Priya Giridharan, Sumit Pandey, Prema Shanmugasundaram, Sabarinathan Ramasamy, Venkateshprabhu Janagaraj, Sivavallinathan Arunachalam, Rahul Sharma, Vaibhav Shah, Bhavani Shankara Bagepally, Joshua Chadwick, Hemant Deepak Shewade, Aniket Chowdhury, Swati Iyer, Raghuram Rao, Sanjay K. Mattoo, Manoj V. Murhekar
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Global Health Research and Policy
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Online Access:https://doi.org/10.1186/s41256-024-00392-9
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author Kathiresan Jeyashree
Jeromie W. V. Thangaraj
Devika Shanmugasundaram
Sri Lakshmi Priya Giridharan
Sumit Pandey
Prema Shanmugasundaram
Sabarinathan Ramasamy
Venkateshprabhu Janagaraj
Sivavallinathan Arunachalam
Rahul Sharma
Vaibhav Shah
Bhavani Shankara Bagepally
Joshua Chadwick
Hemant Deepak Shewade
Aniket Chowdhury
Swati Iyer
Raghuram Rao
Sanjay K. Mattoo
Manoj V. Murhekar
author_facet Kathiresan Jeyashree
Jeromie W. V. Thangaraj
Devika Shanmugasundaram
Sri Lakshmi Priya Giridharan
Sumit Pandey
Prema Shanmugasundaram
Sabarinathan Ramasamy
Venkateshprabhu Janagaraj
Sivavallinathan Arunachalam
Rahul Sharma
Vaibhav Shah
Bhavani Shankara Bagepally
Joshua Chadwick
Hemant Deepak Shewade
Aniket Chowdhury
Swati Iyer
Raghuram Rao
Sanjay K. Mattoo
Manoj V. Murhekar
author_sort Kathiresan Jeyashree
collection DOAJ
description Abstract Background Tuberculosis (TB) poses a significant social and economic burden to households of persons with TB (PwTB). Despite free diagnosis and care under the National TB Elimination Programme (NTEP), individuals often experience significant out-of-pocket expenditure and lost productivity, causing financial catastrophe. We estimated the costs incurred by the PwTB during TB care and identified the factors associated with the costs. Methods In our cross-sectional study, we used multi-stage sampling to select PwTB notified under the NTEP, whose treatment outcome was declared between May 2022 and February 2023. Total patient costs were measured through direct medical, non-medical and indirect costs. Catastrophic costs were defined as expenditure on TB care > 20% of the annual household income. We determined the factors influencing the total cost of TB care using median regression. We plotted concentration curves to depict the equity in distribution of catastrophic costs across income quintiles. We used a cluster-adjusted, generalized model to determine the factors associated with catastrophic costs. Results The mean (SD) age of the 1407 PwTB interviewed was 40.8 (16.8) years. Among them, 865 (61.5%) were male, and 786 (55.9%) were economically active. Thirty-four (2.4%) had Drug Resistant TB (DRTB), and 258 (18.3%) had been hospitalized for TB. The median (Interquartile range [IQR] and 95% confidence interval [CI]) of total costs of TB care was US$386.1 (130.8, 876.9). Direct costs accounted for 34% of the total costs, with a median of US$78.4 (43.3, 153.6), while indirect costs had a median of US$279.8 (18.9,699.4). PwTB < 60 years of age (US$446.1; 370.4, 521.8), without health insurance (US$464.2; 386.7, 541.6), and those hospitalized(US$900.4; 700.2, 1100.6) for TB experienced higher median costs. Catastrophic costs, experienced by 45% of PwTB, followed a pro-poor distribution. Hospitalized PwTB (adjusted prevalence ratio [aPR] = 1.9; 1.6, 2.2) and those notified from the private sector (aPR = 1.4; 1.1, 1.8) were more likely to incur catastrophic costs. Conclusions PwTB in India incur high costs mainly due to lost productivity and hospitalization. Nearly half of them experience catastrophic costs, especially those from poorer economic quintiles. Enabling early notification of TB, expanding the coverage of health insurance schemes to include PwTB, and implementing TB sensitive strategies to address social determinants of TB may significantly reduce catastrophic costs incurred by PwTB.
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spelling doaj-art-00f5ce04b98f45e48a4a33ca4fb3ba102025-08-20T01:56:24ZengBMCGlobal Health Research and Policy2397-06422024-12-019111310.1186/s41256-024-00392-9Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in IndiaKathiresan Jeyashree0Jeromie W. V. Thangaraj1Devika Shanmugasundaram2Sri Lakshmi Priya Giridharan3Sumit Pandey4Prema Shanmugasundaram5Sabarinathan Ramasamy6Venkateshprabhu Janagaraj7Sivavallinathan Arunachalam8Rahul Sharma9Vaibhav Shah10Bhavani Shankara Bagepally11Joshua Chadwick12Hemant Deepak Shewade13Aniket Chowdhury14Swati Iyer15Raghuram Rao16Sanjay K. Mattoo17Manoj V. Murhekar18ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)TB Support Network, WHO Country Office for IndiaTB Support Network, WHO Country Office for IndiaTB Support Network, WHO Country Office for IndiaICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)ICMR-National Institute of Epidemiology (ICMR-NIE)TB Support Network, WHO Country Office for IndiaTB Support Network, WHO Country Office for IndiaCentral TB DivisionCentral TB DivisionICMR-National Institute of Epidemiology (ICMR-NIE)Abstract Background Tuberculosis (TB) poses a significant social and economic burden to households of persons with TB (PwTB). Despite free diagnosis and care under the National TB Elimination Programme (NTEP), individuals often experience significant out-of-pocket expenditure and lost productivity, causing financial catastrophe. We estimated the costs incurred by the PwTB during TB care and identified the factors associated with the costs. Methods In our cross-sectional study, we used multi-stage sampling to select PwTB notified under the NTEP, whose treatment outcome was declared between May 2022 and February 2023. Total patient costs were measured through direct medical, non-medical and indirect costs. Catastrophic costs were defined as expenditure on TB care > 20% of the annual household income. We determined the factors influencing the total cost of TB care using median regression. We plotted concentration curves to depict the equity in distribution of catastrophic costs across income quintiles. We used a cluster-adjusted, generalized model to determine the factors associated with catastrophic costs. Results The mean (SD) age of the 1407 PwTB interviewed was 40.8 (16.8) years. Among them, 865 (61.5%) were male, and 786 (55.9%) were economically active. Thirty-four (2.4%) had Drug Resistant TB (DRTB), and 258 (18.3%) had been hospitalized for TB. The median (Interquartile range [IQR] and 95% confidence interval [CI]) of total costs of TB care was US$386.1 (130.8, 876.9). Direct costs accounted for 34% of the total costs, with a median of US$78.4 (43.3, 153.6), while indirect costs had a median of US$279.8 (18.9,699.4). PwTB < 60 years of age (US$446.1; 370.4, 521.8), without health insurance (US$464.2; 386.7, 541.6), and those hospitalized(US$900.4; 700.2, 1100.6) for TB experienced higher median costs. Catastrophic costs, experienced by 45% of PwTB, followed a pro-poor distribution. Hospitalized PwTB (adjusted prevalence ratio [aPR] = 1.9; 1.6, 2.2) and those notified from the private sector (aPR = 1.4; 1.1, 1.8) were more likely to incur catastrophic costs. Conclusions PwTB in India incur high costs mainly due to lost productivity and hospitalization. Nearly half of them experience catastrophic costs, especially those from poorer economic quintiles. Enabling early notification of TB, expanding the coverage of health insurance schemes to include PwTB, and implementing TB sensitive strategies to address social determinants of TB may significantly reduce catastrophic costs incurred by PwTB.https://doi.org/10.1186/s41256-024-00392-9Costs of TB careCatastrophic costsDirect costsIndirect costsIndia
spellingShingle Kathiresan Jeyashree
Jeromie W. V. Thangaraj
Devika Shanmugasundaram
Sri Lakshmi Priya Giridharan
Sumit Pandey
Prema Shanmugasundaram
Sabarinathan Ramasamy
Venkateshprabhu Janagaraj
Sivavallinathan Arunachalam
Rahul Sharma
Vaibhav Shah
Bhavani Shankara Bagepally
Joshua Chadwick
Hemant Deepak Shewade
Aniket Chowdhury
Swati Iyer
Raghuram Rao
Sanjay K. Mattoo
Manoj V. Murhekar
Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India
Global Health Research and Policy
Costs of TB care
Catastrophic costs
Direct costs
Indirect costs
India
title Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India
title_full Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India
title_fullStr Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India
title_full_unstemmed Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India
title_short Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India
title_sort cost of tb care and equity in distribution of catastrophic tb care costs across income quintiles in india
topic Costs of TB care
Catastrophic costs
Direct costs
Indirect costs
India
url https://doi.org/10.1186/s41256-024-00392-9
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