Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analyses

Objective To explore the risk factors of pulmonary hypertension(PH)in hemodialysis.Methods Retrospective analysis was performed for clinical data of 91 patients with hemodialysis PH.And factorial and cluster analyses were conducted for examining the risk factors of PH in hemodialysis.Results Eleven...

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Main Authors: Liu Xin-wu, Zeng Huan, Liao Bing-qing, Zhao Cheng-bo, Wang Run-xiu
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2021-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57902130&Fpath=home&index=0
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author Liu Xin-wu
Zeng Huan
Liao Bing-qing
Zhao Cheng-bo
Wang Run-xiu
author_facet Liu Xin-wu
Zeng Huan
Liao Bing-qing
Zhao Cheng-bo
Wang Run-xiu
author_sort Liu Xin-wu
collection DOAJ
description Objective To explore the risk factors of pulmonary hypertension(PH)in hemodialysis.Methods Retrospective analysis was performed for clinical data of 91 patients with hemodialysis PH.And factorial and cluster analyses were conducted for examining the risk factors of PH in hemodialysis.Results Eleven unrelated common factors were extracted from 15 parameters by factor analysis.These 11 common factors represented 90.32% of the information of original parameters.After rotation, it could reflect age, gender, anemic status, protein metabolism, lipid metabolism, renal function, inflammation & fibrinolysis status, nutritional status and parathyroid hormone level, etc.And then the results were divided into four categories by cluster analysis: male aged under 60 years, male aged above 60 years, female aged under 60 years and female aged above 60 years.There were varying degrees of anemia, plasma fibrinogen was higher in different degrees, males were significantly more than females and the number of patients aged above 60 years increased significantly.At the same time, the levels of ferritin, blood phosphorus and parathyroid hormone were higher in most patients in categories 2/3/4.Conclusions Anemia and high plasma fibrinogen are important factors in PH patients on hemodialysis.Age and gender may be risk factors.Ferritin, blood phosphorus and parathyroid hormone are potential risk factors in patients with hemodialysis PH.
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publisher Editorial Department of Journal of Clinical Nephrology
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spelling doaj-art-00ea1cef963140f1b5f43badca5f57fd2025-08-20T02:16:13ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-012191191757902130Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analysesLiu Xin-wuZeng HuanLiao Bing-qingZhao Cheng-boWang Run-xiuObjective To explore the risk factors of pulmonary hypertension(PH)in hemodialysis.Methods Retrospective analysis was performed for clinical data of 91 patients with hemodialysis PH.And factorial and cluster analyses were conducted for examining the risk factors of PH in hemodialysis.Results Eleven unrelated common factors were extracted from 15 parameters by factor analysis.These 11 common factors represented 90.32% of the information of original parameters.After rotation, it could reflect age, gender, anemic status, protein metabolism, lipid metabolism, renal function, inflammation & fibrinolysis status, nutritional status and parathyroid hormone level, etc.And then the results were divided into four categories by cluster analysis: male aged under 60 years, male aged above 60 years, female aged under 60 years and female aged above 60 years.There were varying degrees of anemia, plasma fibrinogen was higher in different degrees, males were significantly more than females and the number of patients aged above 60 years increased significantly.At the same time, the levels of ferritin, blood phosphorus and parathyroid hormone were higher in most patients in categories 2/3/4.Conclusions Anemia and high plasma fibrinogen are important factors in PH patients on hemodialysis.Age and gender may be risk factors.Ferritin, blood phosphorus and parathyroid hormone are potential risk factors in patients with hemodialysis PH.http://www.lcszb.com/thesisDetails?columnId=57902130&Fpath=home&index=0HemodialysisPulmonary hypertensionFactorial analysisCluster analysis
spellingShingle Liu Xin-wu
Zeng Huan
Liao Bing-qing
Zhao Cheng-bo
Wang Run-xiu
Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analyses
Linchuang shenzangbing zazhi
Hemodialysis
Pulmonary hypertension
Factorial analysis
Cluster analysis
title Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analyses
title_full Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analyses
title_fullStr Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analyses
title_full_unstemmed Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analyses
title_short Prediction of risk factors in hemodialysis patients with pulmonary hypertension: combined application of factorial and cluster analyses
title_sort prediction of risk factors in hemodialysis patients with pulmonary hypertension combined application of factorial and cluster analyses
topic Hemodialysis
Pulmonary hypertension
Factorial analysis
Cluster analysis
url http://www.lcszb.com/thesisDetails?columnId=57902130&Fpath=home&index=0
work_keys_str_mv AT liuxinwu predictionofriskfactorsinhemodialysispatientswithpulmonaryhypertensioncombinedapplicationoffactorialandclusteranalyses
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AT liaobingqing predictionofriskfactorsinhemodialysispatientswithpulmonaryhypertensioncombinedapplicationoffactorialandclusteranalyses
AT zhaochengbo predictionofriskfactorsinhemodialysispatientswithpulmonaryhypertensioncombinedapplicationoffactorialandclusteranalyses
AT wangrunxiu predictionofriskfactorsinhemodialysispatientswithpulmonaryhypertensioncombinedapplicationoffactorialandclusteranalyses