Chemical Space for Peptide-based Antimicrobials

Chemical Space for Peptide-based Antimicrobials

Multidrug-resistant (MDR) bacteria represent a global public health threat, and antimicrobial peptides (AMPs), derived from naturally occurring linear or cyclic peptides, can provide the solution. However, most AMPs are sensitive to proteases and have poor pharmacokinetics. The EU-funded ERC Advance...

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Bibliographic Details
Main Authors: Markus Orsi, Hippolyte Personne, Etienne Bonvin, Thierry Paschoud, Basak Olcay, Xiaoling Hu, Sacha Javor, Jean-Louis Reymond
Format: Article
Language:deu
Published: Swiss Chemical Society 2024-10-01
Series:CHIMIA
Subjects:
Antimicrobial peptides
Antimicrobial resistance
Chemical space
Peptoids
Virtual screening
Online Access:https://www.chimia.ch/chimia/article/view/7347
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https://www.chimia.ch/chimia/article/view/7347

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