Latex allergy and associated risk factors in a group of Turkish patients with spina bifida

Allergic reactions to latex are common in patients with spina bifida. Its incidence varies between 28% and 67%. The aim of this study was to investigate the incidence of latex allergy and its risk factors in patients with spina bifida in Izmir, Turkey. Forty-six patients (24 male, mean age 10...

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Main Authors: Okan Gülbahar, Remziye Tanaç, Ali Kokuludağ, Figen Gülen, Aytül Sin, Demet Can, Ibrahim Ulman, Nihal Mete, Esen Demir, Filiz Sebik
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2004-07-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2807
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author Okan Gülbahar
Remziye Tanaç
Ali Kokuludağ
Figen Gülen
Aytül Sin
Demet Can
Ibrahim Ulman
Nihal Mete
Esen Demir
Filiz Sebik
author_facet Okan Gülbahar
Remziye Tanaç
Ali Kokuludağ
Figen Gülen
Aytül Sin
Demet Can
Ibrahim Ulman
Nihal Mete
Esen Demir
Filiz Sebik
author_sort Okan Gülbahar
collection DOAJ
description Allergic reactions to latex are common in patients with spina bifida. Its incidence varies between 28% and 67%. The aim of this study was to investigate the incidence of latex allergy and its risk factors in patients with spina bifida in Izmir, Turkey. Forty-six patients (24 male, mean age 10 years) were included in the study. A questionnaire was completed and skin prick tests with latex solution and cross-reacting foods were performed. Total IgE levels, specific IgE to common aeroallergens (Phadiotop), and latex specific IgE levels were measured. Patients with positive skin test reaction and/or who had specific IgE to latex without clinical symptoms were considered as sensitive to latex. The patients who also had clinical symptoms with latex exposure were diagnosed as allergic to latex. Latex sensitivity was found in 5/46 patients (10.8%). Only two patients had latex allergy (4.3%). Total IgE levels were higher (median 157 vs. 40 kU/L, p=0.012) and the duration of clean intermittent catheterization was longer insensitized patients when compared to non-sensitized patients (median 8 vs. 3 years, p=0.015). Specific IgE to common aeroallergens and positive skin prick test to cross-reacting foods were more prevalent in sensitized than in non-sensitized patients (p=0.02 and 0.015, respectively). The incidence of latex allergy in our group was lower than reported in the literature. This result may be due to the low number of surgical interventions. High levels of total IgE, positive Phadiotop, positive skin prick test to cross-reacting foods and the duration of clean intermittent catheterization are the risk factors for latex sensitivity in patients with spina bifida.
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spelling doaj-art-00cba8e4cdf14b239dc63ed9de37dd6b2025-08-20T03:01:17ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212004-07-01463Latex allergy and associated risk factors in a group of Turkish patients with spina bifidaOkan Gülbahar0Remziye TanaçAli KokuludağFigen GülenAytül SinDemet CanIbrahim UlmanNihal MeteEsen DemirFiliz SebikDepartment of Internal Medicine, Ege University Faculty of Medicine, Izmir, Turkey. Allergic reactions to latex are common in patients with spina bifida. Its incidence varies between 28% and 67%. The aim of this study was to investigate the incidence of latex allergy and its risk factors in patients with spina bifida in Izmir, Turkey. Forty-six patients (24 male, mean age 10 years) were included in the study. A questionnaire was completed and skin prick tests with latex solution and cross-reacting foods were performed. Total IgE levels, specific IgE to common aeroallergens (Phadiotop), and latex specific IgE levels were measured. Patients with positive skin test reaction and/or who had specific IgE to latex without clinical symptoms were considered as sensitive to latex. The patients who also had clinical symptoms with latex exposure were diagnosed as allergic to latex. Latex sensitivity was found in 5/46 patients (10.8%). Only two patients had latex allergy (4.3%). Total IgE levels were higher (median 157 vs. 40 kU/L, p=0.012) and the duration of clean intermittent catheterization was longer insensitized patients when compared to non-sensitized patients (median 8 vs. 3 years, p=0.015). Specific IgE to common aeroallergens and positive skin prick test to cross-reacting foods were more prevalent in sensitized than in non-sensitized patients (p=0.02 and 0.015, respectively). The incidence of latex allergy in our group was lower than reported in the literature. This result may be due to the low number of surgical interventions. High levels of total IgE, positive Phadiotop, positive skin prick test to cross-reacting foods and the duration of clean intermittent catheterization are the risk factors for latex sensitivity in patients with spina bifida. https://turkjpediatr.org/article/view/2807
spellingShingle Okan Gülbahar
Remziye Tanaç
Ali Kokuludağ
Figen Gülen
Aytül Sin
Demet Can
Ibrahim Ulman
Nihal Mete
Esen Demir
Filiz Sebik
Latex allergy and associated risk factors in a group of Turkish patients with spina bifida
The Turkish Journal of Pediatrics
title Latex allergy and associated risk factors in a group of Turkish patients with spina bifida
title_full Latex allergy and associated risk factors in a group of Turkish patients with spina bifida
title_fullStr Latex allergy and associated risk factors in a group of Turkish patients with spina bifida
title_full_unstemmed Latex allergy and associated risk factors in a group of Turkish patients with spina bifida
title_short Latex allergy and associated risk factors in a group of Turkish patients with spina bifida
title_sort latex allergy and associated risk factors in a group of turkish patients with spina bifida
url https://turkjpediatr.org/article/view/2807
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