Evaluating Field Stain for Rapid On-Site Evaluation in Fine Needle Aspiratinn Cytology of Breast Lesions: Diagnostic Utility with May-Grünwald Giemsa Staining
Introduction: Fine Needle Aspiration (FNA) cytology is a well-established essential, basic diagnostic technique for investigating lumps and lesions at various anatomic sites. While performing FNA of the breast lumps a quick or rapid result is desirable to know the nature of the lump and allay t...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Prathima Institute of Medical Sciences
2025-04-01
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| Series: | Perspectives In Medical Research |
| Online Access: | https://www.pimr.org.in/2025-vol13-issue-1/Original_Article_Swapnil_Rose_PIMR.pdf |
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| Summary: | Introduction: Fine Needle Aspiration (FNA) cytology is
a well-established essential, basic diagnostic technique for
investigating lumps and lesions at various anatomic sites.
While performing FNA of the breast lumps a quick or rapid
result is desirable to know the nature of the lump and
allay the anxiety of the patient. Rapid On-Site Evaluation
(ROSE) is useful to evaluate the cytological smears within
a few minutes. This study aims to evaluate the utility
of Field’s stain in ROSE of breast lesions in arriving at
a diagnosis and its comparison to routine MGG (May
Grünwald Giemsa) stain. Materials and methods: This
prospective observational study was conducted from July
2023 to December 2023 at a tertiary care center. A total
of 89 cases with breast lumps were included. Previously
diagnosed cases were excluded. All the cases were evaluated
by ROSE using Field’s stain for preliminary diagnosis and
compared later with MGG stain for final diagnosis. The
categorizaƟon of cases was done as per IAC Yokohama
System and further management was advised accordingly.
Results: After first and repeat aspiration, 62 (69.6%) cases
were categorized as benign, 12 (13.4%) cases were found to
be malignant whereas 8 (8.9%), 5 (5.6%), 2 (2.24%) cases
were included in the suspicious, atypical and insufficient
categories respectively. Categorization of the breast lumps
by ROSE using Field stain was in complete agreement with
the MGG stained smears and the final FNA diagnosis and
showed no discrepancy. Conclusion: The use of Field’s stain
for ROSE of breast lumps had comparable staining quality
to MGG which resulted in accurate correlaƟon between
provisional and final cytologic diagnoses with the added
advantage of rapid turnaround Ɵme. Field stain was hence
found to be reliable, cost effecƟve and Ɵme saving when
used for ROSE of breast lumps. Hence the use of this readily
available and affordable stain for ROSE of FNA smears,
especially of breast lumps, can prove to be highly beneficial
for prompt categorization and triaging of patients.
KEYWORDS: Rapid on site evaluation, Breast, Field Stain,
Prompt Categorization, Triage |
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| ISSN: | 2348-1447 2348-229X |