PRMT1-methylated MSX1 phase separates to control palate development

PRMT1-methylated MSX1 phase separates to control palate development

Abstract Little is known about the regulation and function of phase separation in craniofacial developmental disorders. MSX1 mutations are associated with human cleft palate, the most common craniofacial birth defect. Here, we show that MSX1 phase separation is a vertebrate-conserved mechanism under...

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Bibliographic Details
Main Authors: Li Meng, Yucheng Jiang, Jiawen You, Yatao Chen, Shuyu Guo, Liming Chen, Junqing Ma
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56327-6
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