Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest Iran

Background. The impact of COVID-19 on the neonatal population is still mysterious. This study is aimed at reporting the prevalence of COVID-19 and its clinical characteristics and outcomes among neonates in Iran. Methods. We conducted a retrospective cohort including 25 neonates who had COVID-19 inf...

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Main Authors: Najmeh Maharlouei, Arash Khojasteh Zonoozi, Zaynab Noeizad, Atila Erami, Hamidreza Parsa, Zahra Eskandari Kootahi, Sara Raji, Kamran B. Lankarani
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:International Journal of Pediatrics
Online Access:http://dx.doi.org/10.1155/2023/7095326
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author Najmeh Maharlouei
Arash Khojasteh Zonoozi
Zaynab Noeizad
Atila Erami
Hamidreza Parsa
Zahra Eskandari Kootahi
Sara Raji
Kamran B. Lankarani
author_facet Najmeh Maharlouei
Arash Khojasteh Zonoozi
Zaynab Noeizad
Atila Erami
Hamidreza Parsa
Zahra Eskandari Kootahi
Sara Raji
Kamran B. Lankarani
author_sort Najmeh Maharlouei
collection DOAJ
description Background. The impact of COVID-19 on the neonatal population is still mysterious. This study is aimed at reporting the prevalence of COVID-19 and its clinical characteristics and outcomes among neonates in Iran. Methods. We conducted a retrospective cohort including 25 neonates who had COVID-19 infection confirmed by reverse transcription polymerase chain reaction (RT-PCR). Based on neonates’ hospitalization records, data regarding neonatal and maternal characteristics and clinical and paraclinical findings were extracted. Results. In Fars Province, the incidence of COVID-19 among neonates was 47.5 per 100000 living births in one year. From 25 neonates, 20 cases (80%) were recovered, while five cases (20%) died, and all of them were symptomatic. Nine cases (37.5%) were preterm, and two cases (22.2%) belonged to deceased neonates. Four out of five deceased neonates (80%) suffered from congenital abnormalities, and all required respiratory support in the course of their disease progression. Also, 18 neonates (72%) were admitted to NICU. Moreover, the COVID-19 RT-PCR test of nine mothers (43.7%) became positive. Conclusions. This study showed that the incidence of confirmed and symptomatic SARS-CoV-2 infection among neonates in the Fars Province of Iran over one year was 47.5 per 100000 living births. Thoroughly evaluating the epidemiological factors associated with COVID-19, such as underlying health conditions and family history of COVID-19, is crucial in properly managing neonates during the pandemic and increasing awareness.
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spelling doaj-art-00c08dbe9e6a4c13be42d65ac8c4249e2025-08-20T03:22:31ZengWileyInternational Journal of Pediatrics1687-97592023-01-01202310.1155/2023/7095326Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest IranNajmeh Maharlouei0Arash Khojasteh Zonoozi1Zaynab Noeizad2Atila Erami3Hamidreza Parsa4Zahra Eskandari Kootahi5Sara Raji6Kamran B. Lankarani7Community MedicineStudent Research CommitteeDepartment of Child and Infant HealthDepartment of Child and Infant HealthDepartment of Child and Infant HealthDepartment of Child and Infant HealthPersian Cohort Research CenterInternal MedicineBackground. The impact of COVID-19 on the neonatal population is still mysterious. This study is aimed at reporting the prevalence of COVID-19 and its clinical characteristics and outcomes among neonates in Iran. Methods. We conducted a retrospective cohort including 25 neonates who had COVID-19 infection confirmed by reverse transcription polymerase chain reaction (RT-PCR). Based on neonates’ hospitalization records, data regarding neonatal and maternal characteristics and clinical and paraclinical findings were extracted. Results. In Fars Province, the incidence of COVID-19 among neonates was 47.5 per 100000 living births in one year. From 25 neonates, 20 cases (80%) were recovered, while five cases (20%) died, and all of them were symptomatic. Nine cases (37.5%) were preterm, and two cases (22.2%) belonged to deceased neonates. Four out of five deceased neonates (80%) suffered from congenital abnormalities, and all required respiratory support in the course of their disease progression. Also, 18 neonates (72%) were admitted to NICU. Moreover, the COVID-19 RT-PCR test of nine mothers (43.7%) became positive. Conclusions. This study showed that the incidence of confirmed and symptomatic SARS-CoV-2 infection among neonates in the Fars Province of Iran over one year was 47.5 per 100000 living births. Thoroughly evaluating the epidemiological factors associated with COVID-19, such as underlying health conditions and family history of COVID-19, is crucial in properly managing neonates during the pandemic and increasing awareness.http://dx.doi.org/10.1155/2023/7095326
spellingShingle Najmeh Maharlouei
Arash Khojasteh Zonoozi
Zaynab Noeizad
Atila Erami
Hamidreza Parsa
Zahra Eskandari Kootahi
Sara Raji
Kamran B. Lankarani
Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest Iran
International Journal of Pediatrics
title Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest Iran
title_full Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest Iran
title_fullStr Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest Iran
title_full_unstemmed Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest Iran
title_short Incidence, Clinical Features, and Outcomes of the Confirmed Neonatal COVID-19 Infection in the Southwest Iran
title_sort incidence clinical features and outcomes of the confirmed neonatal covid 19 infection in the southwest iran
url http://dx.doi.org/10.1155/2023/7095326
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