Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxide
The current study dealt with using of hydrogen peroxide with 0.5% with drinking water to induce state of oxidative stress in male rats and estimate the ability of different concentrations of the aqueous extract of asparagus officinalis to reduce the effects of oxidative stress during periods 0,15,...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tikrit University
2023-01-01
|
| Series: | Tikrit Journal of Pure Science |
| Subjects: | |
| Online Access: | https://tjpsj.org/index.php/tjps/article/view/775 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849320910446657536 |
|---|---|
| author | Yaser A.M. Sulaiman , Al-saeedy, Khalid. A. H. Moayad M.Y. Al-Anzy |
| author_facet | Yaser A.M. Sulaiman , Al-saeedy, Khalid. A. H. Moayad M.Y. Al-Anzy |
| author_sort | Yaser A.M. Sulaiman |
| collection | DOAJ |
| description |
The current study dealt with using of hydrogen peroxide with 0.5% with drinking water to induce state of oxidative stress in male rats and estimate the ability of different concentrations of the aqueous extract of asparagus officinalis to reduce the effects of oxidative stress during periods 0,15,30 days by measuring the following parameters in serum: Glutathione(GSH), Malondialdehyde (MDA), the activity of super oxide dismutase enzyme (SOD) and the peroxynitrate radical (ONOO).
Fifty male rats with the age of 3-4 months and weight of 300-400 gm were distributed into 5 groups: group (1): control group received drinking tap water, group (2): treated with H2O2 0.5% in drinking water, group (3): treated with H2O2 and asparagus officinalis 5%, group (4): treated with H2O2 and asparagus officinalis 10%, group (5): treated with H2O2 and asparagus officinalis 20% . Hydrogen peroxide treatment led to a significant decrease (P <0.05) of the GSH and SOD activities and increase of the MDA and ONOO levels in the serum during treatment periods compared with the control group. The results of using different concentrations of aqueous extract of asparagus on rats revealed similar effects but not identical in the protection from the oxidative stress induced by Hydrogen Peroxide , because its effect was affected on the level of GSH, SOD, MDA and ONOO levels in the blood serum in different experiment period.
|
| format | Article |
| id | doaj-art-00bceaef33f04b84998a3cd37460274e |
| institution | Kabale University |
| issn | 1813-1662 2415-1726 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Tikrit University |
| record_format | Article |
| series | Tikrit Journal of Pure Science |
| spelling | doaj-art-00bceaef33f04b84998a3cd37460274e2025-08-20T03:49:55ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262023-01-0122510.25130/tjps.v22i5.775Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxideYaser A.M. Sulaiman, Al-saeedy, Khalid. A. H.Moayad M.Y. Al-Anzy The current study dealt with using of hydrogen peroxide with 0.5% with drinking water to induce state of oxidative stress in male rats and estimate the ability of different concentrations of the aqueous extract of asparagus officinalis to reduce the effects of oxidative stress during periods 0,15,30 days by measuring the following parameters in serum: Glutathione(GSH), Malondialdehyde (MDA), the activity of super oxide dismutase enzyme (SOD) and the peroxynitrate radical (ONOO). Fifty male rats with the age of 3-4 months and weight of 300-400 gm were distributed into 5 groups: group (1): control group received drinking tap water, group (2): treated with H2O2 0.5% in drinking water, group (3): treated with H2O2 and asparagus officinalis 5%, group (4): treated with H2O2 and asparagus officinalis 10%, group (5): treated with H2O2 and asparagus officinalis 20% . Hydrogen peroxide treatment led to a significant decrease (P <0.05) of the GSH and SOD activities and increase of the MDA and ONOO levels in the serum during treatment periods compared with the control group. The results of using different concentrations of aqueous extract of asparagus on rats revealed similar effects but not identical in the protection from the oxidative stress induced by Hydrogen Peroxide , because its effect was affected on the level of GSH, SOD, MDA and ONOO levels in the blood serum in different experiment period. https://tjpsj.org/index.php/tjps/article/view/775asparagus officinalisoxidative stressGlutathione(GSH)Malondialdehyde (MDA)super oxide dismutase enzyme (SOD)peroxynitrate (ONOO) |
| spellingShingle | Yaser A.M. Sulaiman , Al-saeedy, Khalid. A. H. Moayad M.Y. Al-Anzy Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxide Tikrit Journal of Pure Science asparagus officinalis oxidative stress Glutathione(GSH) Malondialdehyde (MDA) super oxide dismutase enzyme (SOD) peroxynitrate (ONOO) |
| title | Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxide |
| title_full | Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxide |
| title_fullStr | Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxide |
| title_full_unstemmed | Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxide |
| title_short | Effect of aqueous extract of Asparagus officinalis on some Antioxidants in Rats Exposed to Oxidative Stress induced by Hydrogen peroxide |
| title_sort | effect of aqueous extract of asparagus officinalis on some antioxidants in rats exposed to oxidative stress induced by hydrogen peroxide |
| topic | asparagus officinalis oxidative stress Glutathione(GSH) Malondialdehyde (MDA) super oxide dismutase enzyme (SOD) peroxynitrate (ONOO) |
| url | https://tjpsj.org/index.php/tjps/article/view/775 |
| work_keys_str_mv | AT yaseramsulaiman effectofaqueousextractofasparagusofficinalisonsomeantioxidantsinratsexposedtooxidativestressinducedbyhydrogenperoxide AT alsaeedykhalidah effectofaqueousextractofasparagusofficinalisonsomeantioxidantsinratsexposedtooxidativestressinducedbyhydrogenperoxide AT moayadmyalanzy effectofaqueousextractofasparagusofficinalisonsomeantioxidantsinratsexposedtooxidativestressinducedbyhydrogenperoxide |