Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy

Antisynthetase syndrome is a rare multisystem autoimmune disorder which clinically manifests with myositis, arthritis, interstitial lung disease, Raynaud phenomenon, and skin hyperkeratosis. Lung involvement represents the most severe form of disease and has rarely been reported in pregnancy. We pre...

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Main Authors: Catalina I. Dumitrascu, David A. Olsen, Katherine W. Arendt, Carl H. Rose, Emily E. Sharpe
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2021/1150394
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author Catalina I. Dumitrascu
David A. Olsen
Katherine W. Arendt
Carl H. Rose
Emily E. Sharpe
author_facet Catalina I. Dumitrascu
David A. Olsen
Katherine W. Arendt
Carl H. Rose
Emily E. Sharpe
author_sort Catalina I. Dumitrascu
collection DOAJ
description Antisynthetase syndrome is a rare multisystem autoimmune disorder which clinically manifests with myositis, arthritis, interstitial lung disease, Raynaud phenomenon, and skin hyperkeratosis. Lung involvement represents the most severe form of disease and has rarely been reported in pregnancy. We present the case of a 22-year-old woman with antisynthetase syndrome and severe restrictive pulmonary disease who experienced a successful pregnancy and delivery. We discuss anesthetic considerations and highlight the importance of a multidisciplinary team approach in caring for parturients with multifactorial medical conditions.
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institution Kabale University
issn 2090-6382
2090-6390
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Anesthesiology
spelling doaj-art-00bc2aed574e44f09a1c36bffb88c9912025-02-03T05:43:47ZengWileyCase Reports in Anesthesiology2090-63822090-63902021-01-01202110.1155/2021/11503941150394Antisynthetase Syndrome with Severe Interstitial Lung Disease in PregnancyCatalina I. Dumitrascu0David A. Olsen1Katherine W. Arendt2Carl H. Rose3Emily E. Sharpe4Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 5777 E Mayo Blvd, Phoenix, AZ 85054, USADepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USADepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USADepartment of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USADepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USAAntisynthetase syndrome is a rare multisystem autoimmune disorder which clinically manifests with myositis, arthritis, interstitial lung disease, Raynaud phenomenon, and skin hyperkeratosis. Lung involvement represents the most severe form of disease and has rarely been reported in pregnancy. We present the case of a 22-year-old woman with antisynthetase syndrome and severe restrictive pulmonary disease who experienced a successful pregnancy and delivery. We discuss anesthetic considerations and highlight the importance of a multidisciplinary team approach in caring for parturients with multifactorial medical conditions.http://dx.doi.org/10.1155/2021/1150394
spellingShingle Catalina I. Dumitrascu
David A. Olsen
Katherine W. Arendt
Carl H. Rose
Emily E. Sharpe
Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
Case Reports in Anesthesiology
title Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
title_full Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
title_fullStr Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
title_full_unstemmed Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
title_short Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy
title_sort antisynthetase syndrome with severe interstitial lung disease in pregnancy
url http://dx.doi.org/10.1155/2021/1150394
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AT davidaolsen antisynthetasesyndromewithsevereinterstitiallungdiseaseinpregnancy
AT katherinewarendt antisynthetasesyndromewithsevereinterstitiallungdiseaseinpregnancy
AT carlhrose antisynthetasesyndromewithsevereinterstitiallungdiseaseinpregnancy
AT emilyesharpe antisynthetasesyndromewithsevereinterstitiallungdiseaseinpregnancy