Redox-driven regulation of UCHL3/Yuh1 influences mitochondrial health via the NEDD8/Rub1 pathway

The ubiquitin-like protein NEDD8/Rub1 is initially translated as a precursor and undergoes maturation before becoming functional, a process mediated by the ubiquitin hydrolase UCHL3/Yuh1. Across studied organisms, the mature form of NEDD8/Rub1 modifies cullins, the central subunits of CRLs. NEDD8/Ru...

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Bibliographic Details
Main Authors: Soha Issa, Yuval Klein, Eden Berda, Shahaf Saad, Yehonatan Sharaby, Moran Benhar, Elah Pick
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001685
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