In vivo versus in vitro sperm selection
The separation of human spermatozoa is an important step in therapy of human infertility. Given that male fertility is decreasing and, as a result, fertilization techniques based on microinjection of sperm into the cytoplasm are being used more intensively, this question is becoming increasingly...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MRE Press
2025-02-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://oss.jomh.org/files/article/20250228-502/pdf/JOMH2024101802.pdf |
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| Summary: | The separation of human spermatozoa is an important step in therapy of human
infertility. Given that male fertility is decreasing and, as a result,
fertilization techniques based on microinjection of sperm into the cytoplasm are
being used more intensively, this question is becoming increasingly relevant. In
recent years, microfluidic sperm processing techniques have been increasingly
used. These methods are simple and easy to use, however, the question is to what
extent they select the correct sperm. They are essentially based mainly on
motility and do not reflect other navigational approaches such as chemotaxis,
thermotaxis or rheotaxis. This review compares traditional, advances and
novel in vitro methods of sperm separation which are commonly used
during human infertility therapy in context of in vivo sperm separation
in female reproductive system. |
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| ISSN: | 1875-6867 1875-6859 |