Nasopharyngeal necrosis following intensity-modulated radiation therapy of primary nasopharyngeal carcinoma—incidence rate and predictors of risk

Nasopharyngeal necrosis following intensity-modulated radiation therapy of primary nasopharyngeal carcinoma—incidence rate and predictors of risk

Abstract Objectives This study aimed to investigate the incidence of post radiation nasopharyngeal necrosis (PRNN) in primary NPC after intensity modulated radiation therapy (IMRT) and identify the predictors of risk. Methods Data of 5798 NPC patients who received IMRT-based treatment between April...

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Bibliographic Details
Main Authors: Xing-Li Yang, Li Lin, Sha-Sha He, Dan-Wan Wen, Jia Kou, Yan Wang, Xue-Cen Wang, Yong Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Nasopharyngeal necrosis
Nasopharyngeal carcinoma
Intensity modulated radiation therapy
Dose constraint
Least absolute shrinkage and selection operator logistic regression
Online Access:https://doi.org/10.1186/s12885-025-14086-z
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