RNA binding proteins PCBP1 and PCBP2 regulate pancreatic β cell translation

RNA binding proteins PCBP1 and PCBP2 regulate pancreatic β cell translation

Objectives: Tight control of β cell mRNA translation plays a central role in regulating glucose homoeostasis and β cell health. RNA binding proteins (RBPs) impact translational dynamics and function in networks to achieve their regulatory outcomes, yet an understanding of the RBPs and nature of thei...

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Bibliographic Details
Main Authors: Matthew W. Haemmerle, Kirill Batmanov, Sabyasachi Sen, Matthew J. Varney, Alexander T. Utecht, Austin L. Good, Andrea V. Scota, Sarah A. Tersey, Louis R. Ghanem, Caroline C. Philpott, Doris A. Stoffers
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Molecular Metabolism
Subjects:
Diabetes
Post-transcriptional regulation
β cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000821
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