Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study
Background. Currently, both metabolic syndrome and hyperuricaemia have attracted extensive attention in public health. The correlation between uric acid and metabolic syndrome is controversial. Research on the relationship between uric acid and metabolic syndrome in community-dwelling elderly people...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2023/8080578 |
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| author | Guqiao Nie Jing jing Wan Lei Jiang Shu kai Hou Wen Peng |
| author_facet | Guqiao Nie Jing jing Wan Lei Jiang Shu kai Hou Wen Peng |
| author_sort | Guqiao Nie |
| collection | DOAJ |
| description | Background. Currently, both metabolic syndrome and hyperuricaemia have attracted extensive attention in public health. The correlation between uric acid and metabolic syndrome is controversial. Research on the relationship between uric acid and metabolic syndrome in community-dwelling elderly people is relatively lacking. The purpose of this study is to explore the relationship between uric acid and metabolic syndrome in the community-dwelling elderly people. Design. Cross-sectional study. Methods. We collected the physical examination data of 1,267 elderly people in Gutian community in Wuhan and used SPSS IBM 25.0 for data analysis. Correlation and logistic regression analyses were performed, and ROC curves were drawn. Results. The uric acid level of the nonmetabolic syndrome group was lower than that of the metabolic syndrome group (337.31 vs. 381.91 µmol/L; P<0.05). Uric acid was positively correlated with systolic blood pressure (r = 0.177, P<0.001), diastolic blood pressure (r = 0.135, P<0.001), body mass index (r = 0.234, P<0.001), waist circumference (r = 0.283, P<0.001), and triglycerides (r = 0.217, P<0.05). High-density lipoprotein cholesterol (r = −0.268, P<0.001) showed the opposite trend. Logistic regression analysis results suggested that uric acid is a risk factor for metabolic syndrome. The result is described as exp (B) and 95% CI (1.003 [1.001, 1.005]). Based on the receiver operating characteristic curve, we found that the area under the curve of uric acid to diagnose metabolic syndrome was 0.64 (sensitivity: 79.3%, specificity: 45.1%). Conclusion. We observed an association between uric acid levels and metabolic syndrome in the elderly Chinese population. The best threshold value for uric acid in predicting metabolic syndrome diagnosis was 314.5 μmol/l. |
| format | Article |
| id | doaj-art-0090fd6fc6cc45b8ab1c8473df87c14b |
| institution | OA Journals |
| issn | 1687-8345 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-0090fd6fc6cc45b8ab1c8473df87c14b2025-08-20T02:03:13ZengWileyInternational Journal of Endocrinology1687-83452023-01-01202310.1155/2023/8080578Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional StudyGuqiao Nie0Jing jing Wan1Lei Jiang2Shu kai Hou3Wen Peng4Department of General PracticeDepartment of General PracticeDepartment of General PracticeCommunity Health Service CenterDepartment of General PracticeBackground. Currently, both metabolic syndrome and hyperuricaemia have attracted extensive attention in public health. The correlation between uric acid and metabolic syndrome is controversial. Research on the relationship between uric acid and metabolic syndrome in community-dwelling elderly people is relatively lacking. The purpose of this study is to explore the relationship between uric acid and metabolic syndrome in the community-dwelling elderly people. Design. Cross-sectional study. Methods. We collected the physical examination data of 1,267 elderly people in Gutian community in Wuhan and used SPSS IBM 25.0 for data analysis. Correlation and logistic regression analyses were performed, and ROC curves were drawn. Results. The uric acid level of the nonmetabolic syndrome group was lower than that of the metabolic syndrome group (337.31 vs. 381.91 µmol/L; P<0.05). Uric acid was positively correlated with systolic blood pressure (r = 0.177, P<0.001), diastolic blood pressure (r = 0.135, P<0.001), body mass index (r = 0.234, P<0.001), waist circumference (r = 0.283, P<0.001), and triglycerides (r = 0.217, P<0.05). High-density lipoprotein cholesterol (r = −0.268, P<0.001) showed the opposite trend. Logistic regression analysis results suggested that uric acid is a risk factor for metabolic syndrome. The result is described as exp (B) and 95% CI (1.003 [1.001, 1.005]). Based on the receiver operating characteristic curve, we found that the area under the curve of uric acid to diagnose metabolic syndrome was 0.64 (sensitivity: 79.3%, specificity: 45.1%). Conclusion. We observed an association between uric acid levels and metabolic syndrome in the elderly Chinese population. The best threshold value for uric acid in predicting metabolic syndrome diagnosis was 314.5 μmol/l.http://dx.doi.org/10.1155/2023/8080578 |
| spellingShingle | Guqiao Nie Jing jing Wan Lei Jiang Shu kai Hou Wen Peng Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study International Journal of Endocrinology |
| title | Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study |
| title_full | Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study |
| title_fullStr | Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study |
| title_full_unstemmed | Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study |
| title_short | Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study |
| title_sort | correlation analysis between uric acid and metabolic syndrome in the chinese elderly population a cross sectional study |
| url | http://dx.doi.org/10.1155/2023/8080578 |
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