Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread worldwide. SARS-CoV-2 is prone to mutation, resulting in variants with increased transmissibility, pathogenicity, and immune escape capabilities, posing a sig...

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Main Authors: Xia WU, Xiao ZHANG, Jiayi HAN, Fangxiao XING, Bixiong YE
Format: Article
Language:zho
Published: Editorial Office of Chinese Journal of Public Health 2024-11-01
Series:Zhongguo gonggong weisheng
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Online Access:https://www.zgggws.com/article/doi/10.11847/zgggws1144572
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author Xia WU
Xiao ZHANG
Jiayi HAN
Fangxiao XING
Bixiong YE
author_facet Xia WU
Xiao ZHANG
Jiayi HAN
Fangxiao XING
Bixiong YE
author_sort Xia WU
collection DOAJ
description The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread worldwide. SARS-CoV-2 is prone to mutation, resulting in variants with increased transmissibility, pathogenicity, and immune escape capabilities, posing a significant global threat. To effectively monitor new coronavirus infections, it is necessary to develop diverse detection technologies that are accurate, sensitive, or field-usable for variant identification. This article describes the principles of nucleic acid amplification-based detection techniques for SARS-CoV-2 variants and their applications variant identification and differentiation. It also discusses the advantages and disadvantages of these methods and provides a reference for the accurate identification and efficient detection of SARS-CoV-2 variants.
format Article
id doaj-art-008329df27b548229bc9282368568e10
institution Kabale University
issn 1001-0580
language zho
publishDate 2024-11-01
publisher Editorial Office of Chinese Journal of Public Health
record_format Article
series Zhongguo gonggong weisheng
spelling doaj-art-008329df27b548229bc9282368568e102025-01-23T05:12:02ZzhoEditorial Office of Chinese Journal of Public HealthZhongguo gonggong weisheng1001-05802024-11-0140111396140010.11847/zgggws11445721144572Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress reviewXia WU0Xiao ZHANG1Jiayi HAN2Fangxiao XING3Bixiong YE4Water Quality and Health Monitoring Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Key Laboratory of Environment and Population Health, Chinese Center for Disease Control and Prevention, Beijing 10050, ChinaWater Quality and Health Monitoring Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Key Laboratory of Environment and Population Health, Chinese Center for Disease Control and Prevention, Beijing 10050, ChinaWater Quality and Health Monitoring Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Key Laboratory of Environment and Population Health, Chinese Center for Disease Control and Prevention, Beijing 10050, ChinaWater Quality and Health Monitoring Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Key Laboratory of Environment and Population Health, Chinese Center for Disease Control and Prevention, Beijing 10050, ChinaWater Quality and Health Monitoring Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Key Laboratory of Environment and Population Health, Chinese Center for Disease Control and Prevention, Beijing 10050, ChinaThe coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread worldwide. SARS-CoV-2 is prone to mutation, resulting in variants with increased transmissibility, pathogenicity, and immune escape capabilities, posing a significant global threat. To effectively monitor new coronavirus infections, it is necessary to develop diverse detection technologies that are accurate, sensitive, or field-usable for variant identification. This article describes the principles of nucleic acid amplification-based detection techniques for SARS-CoV-2 variants and their applications variant identification and differentiation. It also discusses the advantages and disadvantages of these methods and provides a reference for the accurate identification and efficient detection of SARS-CoV-2 variants.https://www.zgggws.com/article/doi/10.11847/zgggws1144572sars-cov-2variantnucleic acid amplification technique
spellingShingle Xia WU
Xiao ZHANG
Jiayi HAN
Fangxiao XING
Bixiong YE
Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review
Zhongguo gonggong weisheng
sars-cov-2
variant
nucleic acid amplification technique
title Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review
title_full Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review
title_fullStr Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review
title_full_unstemmed Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review
title_short Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review
title_sort nucleic acid amplification based detection methods for sars cov 2 variant detection research progress review
topic sars-cov-2
variant
nucleic acid amplification technique
url https://www.zgggws.com/article/doi/10.11847/zgggws1144572
work_keys_str_mv AT xiawu nucleicacidamplificationbaseddetectionmethodsforsarscov2variantdetectionresearchprogressreview
AT xiaozhang nucleicacidamplificationbaseddetectionmethodsforsarscov2variantdetectionresearchprogressreview
AT jiayihan nucleicacidamplificationbaseddetectionmethodsforsarscov2variantdetectionresearchprogressreview
AT fangxiaoxing nucleicacidamplificationbaseddetectionmethodsforsarscov2variantdetectionresearchprogressreview
AT bixiongye nucleicacidamplificationbaseddetectionmethodsforsarscov2variantdetectionresearchprogressreview