Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread worldwide. SARS-CoV-2 is prone to mutation, resulting in variants with increased transmissibility, pathogenicity, and immune escape capabilities, posing a sig...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Chinese Journal of Public Health
2024-11-01
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| Series: | Zhongguo gonggong weisheng |
| Subjects: | |
| Online Access: | https://www.zgggws.com/article/doi/10.11847/zgggws1144572 |
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| Summary: | The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread worldwide. SARS-CoV-2 is prone to mutation, resulting in variants with increased transmissibility, pathogenicity, and immune escape capabilities, posing a significant global threat. To effectively monitor new coronavirus infections, it is necessary to develop diverse detection technologies that are accurate, sensitive, or field-usable for variant identification. This article describes the principles of nucleic acid amplification-based detection techniques for SARS-CoV-2 variants and their applications variant identification and differentiation. It also discusses the advantages and disadvantages of these methods and provides a reference for the accurate identification and efficient detection of SARS-CoV-2 variants. |
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| ISSN: | 1001-0580 |