Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical Hypoparathyroidism
Objective. This case highlights use of 1-34 PTH continuous infusion in a patient with postsurgical hypoparathyroidism. Method. Clinical presentation and biochemical profile were monitored before and after 1-34 PTH infusion, with notable reduction in pill burden in a patient with postsurgical hypopar...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2021/5593653 |
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| author | Adnan Haider Oksana Symczyk Yadel Couso Taylor Cater Sheree Bryan |
| author_facet | Adnan Haider Oksana Symczyk Yadel Couso Taylor Cater Sheree Bryan |
| author_sort | Adnan Haider |
| collection | DOAJ |
| description | Objective. This case highlights use of 1-34 PTH continuous infusion in a patient with postsurgical hypoparathyroidism. Method. Clinical presentation and biochemical profile were monitored before and after 1-34 PTH infusion, with notable reduction in pill burden in a patient with postsurgical hypoparathyroidism. Results. We present a case of postsurgical hypoparathyroidism following thyroidectomy for Graves disease. The patient was requiring a total of 34 pills daily and, despite medication compliance, her clinical and biochemical control was unsatisfactory. Following initiation of 1-34 PTH in the form of a subcutaneous pump, we were able to stop all calcium supplementation and reduce calcitriol to 0.5 mcg daily. Her current biochemical control as well as quality of life improved significantly on CSPI, calcitriol, and a daily serving of dietary calcium. Conclusion. This case highlights the use of 1-34 PTH either as twice-daily dosing or continuous subcutaneous infusion for adult patients with hypoparathyroidism. |
| format | Article |
| id | doaj-art-00784a39b30d4a92a7e18f6e1b7088fe |
| institution | OA Journals |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-00784a39b30d4a92a7e18f6e1b7088fe2025-08-20T02:03:13ZengWileyCase Reports in Endocrinology2090-65012090-651X2021-01-01202110.1155/2021/55936535593653Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical HypoparathyroidismAdnan Haider0Oksana Symczyk1Yadel Couso2Taylor Cater3Sheree Bryan4Department of Endocrinology, West Virginia University, Morgantown, WV, USADepartment of Endocrinology, West Virginia University, Morgantown, WV, USADepartment of Endocrinology, West Virginia University, Morgantown, WV, USADepartment of Medicine, West Virginia University, Morgantown, WV, USADepartment of Medicine, West Virginia University, Morgantown, WV, USAObjective. This case highlights use of 1-34 PTH continuous infusion in a patient with postsurgical hypoparathyroidism. Method. Clinical presentation and biochemical profile were monitored before and after 1-34 PTH infusion, with notable reduction in pill burden in a patient with postsurgical hypoparathyroidism. Results. We present a case of postsurgical hypoparathyroidism following thyroidectomy for Graves disease. The patient was requiring a total of 34 pills daily and, despite medication compliance, her clinical and biochemical control was unsatisfactory. Following initiation of 1-34 PTH in the form of a subcutaneous pump, we were able to stop all calcium supplementation and reduce calcitriol to 0.5 mcg daily. Her current biochemical control as well as quality of life improved significantly on CSPI, calcitriol, and a daily serving of dietary calcium. Conclusion. This case highlights the use of 1-34 PTH either as twice-daily dosing or continuous subcutaneous infusion for adult patients with hypoparathyroidism.http://dx.doi.org/10.1155/2021/5593653 |
| spellingShingle | Adnan Haider Oksana Symczyk Yadel Couso Taylor Cater Sheree Bryan Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical Hypoparathyroidism Case Reports in Endocrinology |
| title | Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical Hypoparathyroidism |
| title_full | Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical Hypoparathyroidism |
| title_fullStr | Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical Hypoparathyroidism |
| title_full_unstemmed | Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical Hypoparathyroidism |
| title_short | Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1-34 PTH Infusion for Postsurgical Hypoparathyroidism |
| title_sort | desperate times call for desperate measures use of continuous subcutaneous 1 34 pth infusion for postsurgical hypoparathyroidism |
| url | http://dx.doi.org/10.1155/2021/5593653 |
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