Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report

This case report describes a 61-year-old female who developed cutaneous small vessel vasculitis following a calcium-hydroxyapatite-based filler injection. The patient presented with a generalized purpuric and petechial rash, along with arthralgia. A skin biopsy confirmed features consistent with cut...

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Main Authors: Ghassan Barnawi, Sarah Kashkari, Arieh Gomolin, May Chergui, Badia Issa-Chergui, Lisa Iannatone
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251341563
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author Ghassan Barnawi
Sarah Kashkari
Arieh Gomolin
May Chergui
Badia Issa-Chergui
Lisa Iannatone
author_facet Ghassan Barnawi
Sarah Kashkari
Arieh Gomolin
May Chergui
Badia Issa-Chergui
Lisa Iannatone
author_sort Ghassan Barnawi
collection DOAJ
description This case report describes a 61-year-old female who developed cutaneous small vessel vasculitis following a calcium-hydroxyapatite-based filler injection. The patient presented with a generalized purpuric and petechial rash, along with arthralgia. A skin biopsy confirmed features consistent with cutaneous small vessel vasculitis. Treatment with a 6-week prednisone taper resulted in complete symptom resolution. This observation warrants further investigation into the potential role of dermal fillers in triggering inflammatory conditions like cutaneous small vessel vasculitis.
format Article
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institution Kabale University
issn 2050-313X
language English
publishDate 2025-06-01
publisher SAGE Publishing
record_format Article
series SAGE Open Medical Case Reports
spelling doaj-art-00762d0c4e884b0db845fe884c6afa502025-08-20T03:47:12ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-06-011310.1177/2050313X251341563Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case reportGhassan Barnawi0Sarah Kashkari1Arieh Gomolin2May Chergui3Badia Issa-Chergui4Lisa Iannatone5Department of Dermatology, McGill University, Montreal, QC, CanadaDepartment of Dermatology, McGill University, Montreal, QC, CanadaDepartment of Pathology, McGill University, Montreal, QC, CanadaDepartment of Pathology, McGill University, Montreal, QC, CanadaDepartment of Pathology, McGill University, Montreal, QC, CanadaDepartment of Dermatology, McGill University, Montreal, QC, CanadaThis case report describes a 61-year-old female who developed cutaneous small vessel vasculitis following a calcium-hydroxyapatite-based filler injection. The patient presented with a generalized purpuric and petechial rash, along with arthralgia. A skin biopsy confirmed features consistent with cutaneous small vessel vasculitis. Treatment with a 6-week prednisone taper resulted in complete symptom resolution. This observation warrants further investigation into the potential role of dermal fillers in triggering inflammatory conditions like cutaneous small vessel vasculitis.https://doi.org/10.1177/2050313X251341563
spellingShingle Ghassan Barnawi
Sarah Kashkari
Arieh Gomolin
May Chergui
Badia Issa-Chergui
Lisa Iannatone
Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report
SAGE Open Medical Case Reports
title Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report
title_full Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report
title_fullStr Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report
title_full_unstemmed Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report
title_short Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report
title_sort cutaneous small vessel vasculitis following calcium hydroxyapatite filler a rare case report
url https://doi.org/10.1177/2050313X251341563
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