Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review
Petrified ear is a rare clinical entity characterized by the progressive hardening of normal flexible auricular cartilage, leading to partial or complete auricular stiffness. In many cases, it provides a valuable clinical clue that allows the clinician to detect endocrinopathies (particularly Addis...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2025-01-01
|
| Series: | Dermatology Reports |
| Subjects: | |
| Online Access: | https://www.pagepress.org/journals/dr/article/view/10263 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832575492223401984 |
|---|---|
| author | Sebastiano Recalcati Alberto Vassallo Marta Villanova Roberto Lanzi Marco Losa Maria Grazia Patricelli Paola Carrera Fabrizio Fantini |
| author_facet | Sebastiano Recalcati Alberto Vassallo Marta Villanova Roberto Lanzi Marco Losa Maria Grazia Patricelli Paola Carrera Fabrizio Fantini |
| author_sort | Sebastiano Recalcati |
| collection | DOAJ |
| description |
Petrified ear is a rare clinical entity characterized by the progressive hardening of normal flexible auricular cartilage, leading to partial or complete auricular stiffness. In many cases, it provides a valuable clinical clue that allows the clinician to detect endocrinopathies (particularly Addison’s disease) in a patient who has not received a diagnosis. We present the first documented case of petrified ears, which resulted in the diagnosis of both secondary hypoadrenalism and growth hormone deficiency (GHD). Additionally, we review the relevant literature. Petrified ears syndrome is probably an underreported clinical manifestation of other systemic disorders. It may, at times, serve as a useful and simple clinical clue to suspect underlying endocrinopathies even in the absence of typical features.
|
| format | Article |
| id | doaj-art-00680ec262a64dad81aba708d24b6a8f |
| institution | Kabale University |
| issn | 2036-7392 2036-7406 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj-art-00680ec262a64dad81aba708d24b6a8f2025-02-01T01:44:19ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062025-01-0110.4081/dr.2025.10263Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature reviewSebastiano Recalcati0Alberto Vassallo1Marta Villanova2Roberto Lanzi3Marco Losa4Maria Grazia Patricelli5Paola Carrera6Fabrizio Fantini7Dermatology Unit, ASST Lecco, Alessandro Manzoni HospitalInstitute of Endocrine and Metabolic Sciences, Vita-Salute San Raffaele University, MilanInstitute of Endocrine and Metabolic Sciences, Vita-Salute San Raffaele University, MilanInternal Medicine Department, IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, MilanNeurosurgery Department, IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, MilanUnit of Genomics for Human Disease Diagnosis, IRCCS Ospedale San Raffaele, MilanUnit of Genomics for Human Disease Diagnosis, IRCCS Ospedale San Raffaele, MilanDermatology Unit, ASST Lecco, Alessandro Manzoni Hospital Petrified ear is a rare clinical entity characterized by the progressive hardening of normal flexible auricular cartilage, leading to partial or complete auricular stiffness. In many cases, it provides a valuable clinical clue that allows the clinician to detect endocrinopathies (particularly Addison’s disease) in a patient who has not received a diagnosis. We present the first documented case of petrified ears, which resulted in the diagnosis of both secondary hypoadrenalism and growth hormone deficiency (GHD). Additionally, we review the relevant literature. Petrified ears syndrome is probably an underreported clinical manifestation of other systemic disorders. It may, at times, serve as a useful and simple clinical clue to suspect underlying endocrinopathies even in the absence of typical features. https://www.pagepress.org/journals/dr/article/view/10263Petrified earsauricular calcificationmetastatic calcificationendocrinopathiesadrenal insufficiency |
| spellingShingle | Sebastiano Recalcati Alberto Vassallo Marta Villanova Roberto Lanzi Marco Losa Maria Grazia Patricelli Paola Carrera Fabrizio Fantini Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review Dermatology Reports Petrified ears auricular calcification metastatic calcification endocrinopathies adrenal insufficiency |
| title | Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review |
| title_full | Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review |
| title_fullStr | Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review |
| title_full_unstemmed | Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review |
| title_short | Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review |
| title_sort | growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome a case report and literature review |
| topic | Petrified ears auricular calcification metastatic calcification endocrinopathies adrenal insufficiency |
| url | https://www.pagepress.org/journals/dr/article/view/10263 |
| work_keys_str_mv | AT sebastianorecalcati growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview AT albertovassallo growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview AT martavillanova growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview AT robertolanzi growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview AT marcolosa growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview AT mariagraziapatricelli growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview AT paolacarrera growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview AT fabriziofantini growthhormonedeficiencyandsecondaryadrenalinsufficiencyinpetrifiedearssyndromeacasereportandliteraturereview |