Synthesis of Polyfunctionalized 4H-Pyrans
Amberlyst A21 catalyzed one-pot three-component coupling of aldehyde and malononitrile with active methylene compounds such as acetylacetone and ethyl acetoacetate for the synthesis of pharmaceutically important polyfunctionalized 4H-pyrans has been reported. Simple experimental procedure, no chroma...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/785930 |
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| author | Manisha Bihani Pranjal P. Bora Ghanashyam Bez |
| author_facet | Manisha Bihani Pranjal P. Bora Ghanashyam Bez |
| author_sort | Manisha Bihani |
| collection | DOAJ |
| description | Amberlyst A21 catalyzed one-pot three-component coupling of aldehyde and malononitrile with active methylene compounds such as acetylacetone and ethyl acetoacetate for the synthesis of pharmaceutically important polyfunctionalized 4H-pyrans has been reported. Simple experimental procedure, no chromatographic purification, no hazardous organic solvents, easy recovery and reusability of the catalyst, and room temperature reaction conditions are some of the highlights of this protocol for the synthesis of pharmaceutically relevant focused libraries. |
| format | Article |
| id | doaj-art-00660c9d27e44beb90be352aee19fa46 |
| institution | OA Journals |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-00660c9d27e44beb90be352aee19fa462025-08-20T02:03:12ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/785930785930Synthesis of Polyfunctionalized 4H-PyransManisha Bihani0Pranjal P. Bora1Ghanashyam Bez2Department of Chemistry, North Eastern Hill University, Shillong 793022, IndiaDepartment of Chemistry, North Eastern Hill University, Shillong 793022, IndiaDepartment of Chemistry, North Eastern Hill University, Shillong 793022, IndiaAmberlyst A21 catalyzed one-pot three-component coupling of aldehyde and malononitrile with active methylene compounds such as acetylacetone and ethyl acetoacetate for the synthesis of pharmaceutically important polyfunctionalized 4H-pyrans has been reported. Simple experimental procedure, no chromatographic purification, no hazardous organic solvents, easy recovery and reusability of the catalyst, and room temperature reaction conditions are some of the highlights of this protocol for the synthesis of pharmaceutically relevant focused libraries.http://dx.doi.org/10.1155/2013/785930 |
| spellingShingle | Manisha Bihani Pranjal P. Bora Ghanashyam Bez Synthesis of Polyfunctionalized 4H-Pyrans Journal of Chemistry |
| title | Synthesis of Polyfunctionalized 4H-Pyrans |
| title_full | Synthesis of Polyfunctionalized 4H-Pyrans |
| title_fullStr | Synthesis of Polyfunctionalized 4H-Pyrans |
| title_full_unstemmed | Synthesis of Polyfunctionalized 4H-Pyrans |
| title_short | Synthesis of Polyfunctionalized 4H-Pyrans |
| title_sort | synthesis of polyfunctionalized 4h pyrans |
| url | http://dx.doi.org/10.1155/2013/785930 |
| work_keys_str_mv | AT manishabihani synthesisofpolyfunctionalized4hpyrans AT pranjalpbora synthesisofpolyfunctionalized4hpyrans AT ghanashyambez synthesisofpolyfunctionalized4hpyrans |