Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six Cases
Background: <i>Listeria monocytogenes</i>, a Gram-positive intracellular bacillus, causes listeriosis, which is primarily transmitted through contaminated food and vertical transmission. The incidence of the disease is estimated to be between one and ten cases per million globally, with...
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2024-11-01
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| author | Lucía Castaño Frías Carmen Tudela-Littleton Peralta Natalia Segura Oliva María Suárez Arana Celia Cuenca Marín Jesús S. Jiménez López |
| author_facet | Lucía Castaño Frías Carmen Tudela-Littleton Peralta Natalia Segura Oliva María Suárez Arana Celia Cuenca Marín Jesús S. Jiménez López |
| author_sort | Lucía Castaño Frías |
| collection | DOAJ |
| description | Background: <i>Listeria monocytogenes</i>, a Gram-positive intracellular bacillus, causes listeriosis, which is primarily transmitted through contaminated food and vertical transmission. The incidence of the disease is estimated to be between one and ten cases per million globally, with pregnant women being particularly vulnerable. Objective: The aim was to describe the clinical characteristics, management, and outcomes of cases of gestational listeriosis at Hospital Materno Infantil de Málaga in order to improve our understanding, diagnosis, and treatment of this disease. Methods: A retrospective analysis of six confirmed cases of listeriosis was performed in pregnant women or neonates. Diagnostic confirmation was achieved using analytic and microbiological methodologies, including blood cultures and the measurement of C-reactive protein (CRP). Ethical approval was obtained, and clinical data were reviewed for reasons related to consultation, treatment approaches, and complications. Results: The most frequently observed symptoms were fever and abdominal pain, with complications such as intrauterine death and suspected chorioamnionitis. Four patients were treated with antibiotics, leading to improved outcomes. No severe complications such as neurolisteriosis were observed. Conclusions: Pregnant women are more susceptible to <i>L. monocytogenes</i>, which can cause mild maternal symptoms but severe foetal outcomes, including prematurity, foetal death, or neonatal infections. Early diagnosis and prompt treatment are crucial for improving maternal–foetal outcomes. |
| format | Article |
| id | doaj-art-006588a5349745e18c61ef01f7fb825a |
| institution | Kabale University |
| issn | 2076-2607 |
| language | English |
| publishDate | 2024-11-01 |
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| series | Microorganisms |
| spelling | doaj-art-006588a5349745e18c61ef01f7fb825a2024-11-26T18:14:53ZengMDPI AGMicroorganisms2076-26072024-11-011211230610.3390/microorganisms12112306Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six CasesLucía Castaño Frías0Carmen Tudela-Littleton Peralta1Natalia Segura Oliva2María Suárez Arana3Celia Cuenca Marín4Jesús S. Jiménez López5Obstetrics and Gynecology Department, Hospital Materno-Infantil, Hospital Regional Universitario Málaga, Avenue Arroyo de los Ángeles S/N, 29011 Málaga, SpainObstetrics and Gynecology Department, Hospital Materno-Infantil, Hospital Regional Universitario Málaga, Avenue Arroyo de los Ángeles S/N, 29011 Málaga, SpainObstetrics and Gynecology Department, Hospital Materno-Infantil, Hospital Regional Universitario Málaga, Avenue Arroyo de los Ángeles S/N, 29011 Málaga, SpainObstetrics and Gynecology Department, Hospital Materno-Infantil, Hospital Regional Universitario Málaga, Avenue Arroyo de los Ángeles S/N, 29011 Málaga, SpainObstetrics and Gynecology Department, Hospital Materno-Infantil, Hospital Regional Universitario Málaga, Avenue Arroyo de los Ángeles S/N, 29011 Málaga, SpainObstetrics and Gynecology Department, Hospital Materno-Infantil, Hospital Regional Universitario Málaga, Avenue Arroyo de los Ángeles S/N, 29011 Málaga, SpainBackground: <i>Listeria monocytogenes</i>, a Gram-positive intracellular bacillus, causes listeriosis, which is primarily transmitted through contaminated food and vertical transmission. The incidence of the disease is estimated to be between one and ten cases per million globally, with pregnant women being particularly vulnerable. Objective: The aim was to describe the clinical characteristics, management, and outcomes of cases of gestational listeriosis at Hospital Materno Infantil de Málaga in order to improve our understanding, diagnosis, and treatment of this disease. Methods: A retrospective analysis of six confirmed cases of listeriosis was performed in pregnant women or neonates. Diagnostic confirmation was achieved using analytic and microbiological methodologies, including blood cultures and the measurement of C-reactive protein (CRP). Ethical approval was obtained, and clinical data were reviewed for reasons related to consultation, treatment approaches, and complications. Results: The most frequently observed symptoms were fever and abdominal pain, with complications such as intrauterine death and suspected chorioamnionitis. Four patients were treated with antibiotics, leading to improved outcomes. No severe complications such as neurolisteriosis were observed. Conclusions: Pregnant women are more susceptible to <i>L. monocytogenes</i>, which can cause mild maternal symptoms but severe foetal outcomes, including prematurity, foetal death, or neonatal infections. Early diagnosis and prompt treatment are crucial for improving maternal–foetal outcomes.https://www.mdpi.com/2076-2607/12/11/2306<i>Listeria monocytogenes</i>pregnancylisteriosischorioamnionitismiscarriagediagnosis of listeriosis |
| spellingShingle | Lucía Castaño Frías Carmen Tudela-Littleton Peralta Natalia Segura Oliva María Suárez Arana Celia Cuenca Marín Jesús S. Jiménez López Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six Cases Microorganisms <i>Listeria monocytogenes</i> pregnancy listeriosis chorioamnionitis miscarriage diagnosis of listeriosis |
| title | Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six Cases |
| title_full | Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six Cases |
| title_fullStr | Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six Cases |
| title_full_unstemmed | Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six Cases |
| title_short | Case Series of <i>Listeria monocytogenes</i> in Pregnancy: Maternal–Foetal Complications and Clinical Management in Six Cases |
| title_sort | case series of i listeria monocytogenes i in pregnancy maternal foetal complications and clinical management in six cases |
| topic | <i>Listeria monocytogenes</i> pregnancy listeriosis chorioamnionitis miscarriage diagnosis of listeriosis |
| url | https://www.mdpi.com/2076-2607/12/11/2306 |
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