Fusion protein of retinol‐binding protein and albumin domain III reduces liver fibrosis

Fusion protein of retinol‐binding protein and albumin domain III reduces liver fibrosis

Abstract Activated hepatic stellate cells (HSCs) play a key role in liver fibrosis, and inactivating HSCs has been considered a promising therapeutic approach. We previously showed that albumin and its derivative designed for stellate cell‐targeting, retinol‐binding protein–albumin domain III fusion...

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Main Authors: Hongsik Lee, Hyeyeun Jeong, Sangeun Park, Wonbaek Yoo, Soyoung Choi, Kyungmin Choi, Min‐Goo Lee, Mihwa Lee, DaeRyong Cha, Young‐Sik Kim, Jeeyoung Han, Wonkon Kim, Sun‐Hwa Park, Junseo Oh
Format: Article
Language:English
Published: Springer Nature 2015-04-01
Series:EMBO Molecular Medicine
Subjects:
albumin
anti‐fibrotic drug
fibrosis
hepatic stellate cell
retinoic acid
Online Access:https://doi.org/10.15252/emmm.201404527
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