Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potential

Recently, the utilization of natural or herbal products has increased worldwide. Various naturally isolated plant products have been assessed as therapeutics for the treatment of a variety of diseases. Microbes are related to medicinal plants and have enormous potential in the context of promoting p...

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Main Authors: Himani Barthwal, Charu Sharma, Vijay Kumar, Vishal Rajput, Bindu Naik, Shivesh Sharma, Sushila Devi, Vivek Kumar
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Phytomedicine Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667031325001368
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author Himani Barthwal
Charu Sharma
Vijay Kumar
Vishal Rajput
Bindu Naik
Shivesh Sharma
Sushila Devi
Vivek Kumar
author_facet Himani Barthwal
Charu Sharma
Vijay Kumar
Vishal Rajput
Bindu Naik
Shivesh Sharma
Sushila Devi
Vivek Kumar
author_sort Himani Barthwal
collection DOAJ
description Recently, the utilization of natural or herbal products has increased worldwide. Various naturally isolated plant products have been assessed as therapeutics for the treatment of a variety of diseases. Microbes are related to medicinal plants and have enormous potential in the context of promoting plant growth traits and producing active ingredients of therapeutic importance. Bacopa monnieri, also called ‘Brahmi’ and water hyssop, has been utilized extensively in the ayurvedic system of medicine for a long time. Phytochemical investigations of B. monnieri extracts have revealed the occurrence of several active compounds, such as bacosides, alkaloids and triterpenoids. All these active chemical ingredients act as the best memory enhancer and are also used for various illnesses. The microbially mediated production of novel secondary metabolites with key biological activities could be an alternative method to obtain bioactive ingredients. This review highlights the interactions between microbes and the medicinal plant B. monnieri, illuminating the creation of biologically active compounds with medicinal importance within the plant.
format Article
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institution Kabale University
issn 2667-0313
language English
publishDate 2025-11-01
publisher Elsevier
record_format Article
series Phytomedicine Plus
spelling doaj-art-005726ef037a4e6a8feedffdf0bb1c8c2025-08-22T04:58:35ZengElsevierPhytomedicine Plus2667-03132025-11-015410086510.1016/j.phyplu.2025.100865Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potentialHimani Barthwal0Charu Sharma1Vijay Kumar2Vishal Rajput3Bindu Naik4Shivesh Sharma5Sushila Devi6Vivek Kumar7School of Biosciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, IndiaSchool of Biosciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, IndiaSchool of Biosciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, IndiaSchool of Biosciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, IndiaDepartment of Food Science and Technology, Graphic Era (Deemed to be University), Clement Town, Dehradun, IndiaDepartment of Biotechnology, MLN National Institute of Technology, Prayagraj (Allahabad), IndiaDepartment of Microbiology, Himachal Pradesh University, Summer Hill, Shimla, IndiaSchool of Biosciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India; Corresponding author.Recently, the utilization of natural or herbal products has increased worldwide. Various naturally isolated plant products have been assessed as therapeutics for the treatment of a variety of diseases. Microbes are related to medicinal plants and have enormous potential in the context of promoting plant growth traits and producing active ingredients of therapeutic importance. Bacopa monnieri, also called ‘Brahmi’ and water hyssop, has been utilized extensively in the ayurvedic system of medicine for a long time. Phytochemical investigations of B. monnieri extracts have revealed the occurrence of several active compounds, such as bacosides, alkaloids and triterpenoids. All these active chemical ingredients act as the best memory enhancer and are also used for various illnesses. The microbially mediated production of novel secondary metabolites with key biological activities could be an alternative method to obtain bioactive ingredients. This review highlights the interactions between microbes and the medicinal plant B. monnieri, illuminating the creation of biologically active compounds with medicinal importance within the plant.http://www.sciencedirect.com/science/article/pii/S2667031325001368Bacopa monnieriBacosidesBioactive compoundsBrahmiEndophytesPharmaceutical
spellingShingle Himani Barthwal
Charu Sharma
Vijay Kumar
Vishal Rajput
Bindu Naik
Shivesh Sharma
Sushila Devi
Vivek Kumar
Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potential
Phytomedicine Plus
Bacopa monnieri
Bacosides
Bioactive compounds
Brahmi
Endophytes
Pharmaceutical
title Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potential
title_full Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potential
title_fullStr Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potential
title_full_unstemmed Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potential
title_short Bacopa monnieri, a wonder plant in the backyard: Emphasizing the role of the microbiome in increasing its potential
title_sort bacopa monnieri a wonder plant in the backyard emphasizing the role of the microbiome in increasing its potential
topic Bacopa monnieri
Bacosides
Bioactive compounds
Brahmi
Endophytes
Pharmaceutical
url http://www.sciencedirect.com/science/article/pii/S2667031325001368
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