EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS
Aim: to assess efficacy and safety of etanercept in treatment of various types of juvenile idiopathic arthritis in children under conditions of real clinical practice. Patients and methods: 52 children were included into the study, among them 16 were with systemic and 36 with juvenile idiopathic art...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2013-12-01
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| Series: | Вопросы современной педиатрии |
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| Online Access: | https://vsp.spr-journal.ru/jour/article/view/267 |
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| author | O. Yu. Konopel'ko E. S. Zholobova M. N. Nikolaeva O. S. Rozvadovskaya V. Ya. El'yashevich E. Yu. Afonina |
| author_facet | O. Yu. Konopel'ko E. S. Zholobova M. N. Nikolaeva O. S. Rozvadovskaya V. Ya. El'yashevich E. Yu. Afonina |
| author_sort | O. Yu. Konopel'ko |
| collection | DOAJ |
| description | Aim: to assess efficacy and safety of etanercept in treatment of various types of juvenile idiopathic arthritis in children under conditions of real clinical practice. Patients and methods: 52 children were included into the study, among them 16 were with systemic and 36 with juvenile idiopathic arthritis without extra-articular involvement. Results: etanercept treatment was the most efficient in patients with systemic juvenile idiopathic arthritis without extra-articular involvement. In 6 and 12 months of the treatment 50 and 70% improvement according to the ACRpedi criteria were established in 31/36 (86%) and 28/36 (78%) of the patients, respectively. In 24 months in 5 (29%) of 17 children remained in the study remission stage of the diseases was confirmed. Conclusions: etanercept treatment was not associated with significant unfavorable effects, which allows to recommend this drug for treatment of juvenile idiopathic arthritis without extra-articular involvent and resistant to standard anti-rheumatic therapy. |
| format | Article |
| id | doaj-art-004f5088a45d4858b490b7c90e5205ca |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2013-12-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-004f5088a45d4858b490b7c90e5205ca2025-08-20T03:57:26Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352013-12-0112611511910.15690/vsp.v12i6.885267EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITISO. Yu. Konopel'ko0E. S. Zholobova1M. N. Nikolaeva2O. S. Rozvadovskaya3V. Ya. El'yashevich4E. Yu. Afonina5I.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityAim: to assess efficacy and safety of etanercept in treatment of various types of juvenile idiopathic arthritis in children under conditions of real clinical practice. Patients and methods: 52 children were included into the study, among them 16 were with systemic and 36 with juvenile idiopathic arthritis without extra-articular involvement. Results: etanercept treatment was the most efficient in patients with systemic juvenile idiopathic arthritis without extra-articular involvement. In 6 and 12 months of the treatment 50 and 70% improvement according to the ACRpedi criteria were established in 31/36 (86%) and 28/36 (78%) of the patients, respectively. In 24 months in 5 (29%) of 17 children remained in the study remission stage of the diseases was confirmed. Conclusions: etanercept treatment was not associated with significant unfavorable effects, which allows to recommend this drug for treatment of juvenile idiopathic arthritis without extra-articular involvent and resistant to standard anti-rheumatic therapy.https://vsp.spr-journal.ru/jour/article/view/267childrenjuvenile idiopathic arthritisgenetically engineered biological agentsetanercept |
| spellingShingle | O. Yu. Konopel'ko E. S. Zholobova M. N. Nikolaeva O. S. Rozvadovskaya V. Ya. El'yashevich E. Yu. Afonina EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS Вопросы современной педиатрии children juvenile idiopathic arthritis genetically engineered biological agents etanercept |
| title | EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS |
| title_full | EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS |
| title_fullStr | EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS |
| title_full_unstemmed | EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS |
| title_short | EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS |
| title_sort | efficacy of etanercept in treatment of various types of juvenile idiopathic arthritis |
| topic | children juvenile idiopathic arthritis genetically engineered biological agents etanercept |
| url | https://vsp.spr-journal.ru/jour/article/view/267 |
| work_keys_str_mv | AT oyukonopelko efficacyofetanerceptintreatmentofvarioustypesofjuvenileidiopathicarthritis AT eszholobova efficacyofetanerceptintreatmentofvarioustypesofjuvenileidiopathicarthritis AT mnnikolaeva efficacyofetanerceptintreatmentofvarioustypesofjuvenileidiopathicarthritis AT osrozvadovskaya efficacyofetanerceptintreatmentofvarioustypesofjuvenileidiopathicarthritis AT vyaelyashevich efficacyofetanerceptintreatmentofvarioustypesofjuvenileidiopathicarthritis AT eyuafonina efficacyofetanerceptintreatmentofvarioustypesofjuvenileidiopathicarthritis |