The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis
Background: Postoperative pain is a significant yet inadequately managed complication following surgery, and auriculotherapy to alleviate acute postoperative pain (APP) and reduce the use of opioids remains controversial. Methods: We searched the MEDLINE, Web of Science, Embase, Cochrane Library, CI...
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Elsevier
2025-03-01
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| Series: | Complementary Therapies in Medicine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0965229924001006 |
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| author | Guilin Zhang Guixing Xu Yao Tang Lingxue Zhang Xi Chen Xingyu Liang Ling Zhao Dehua Li |
| author_facet | Guilin Zhang Guixing Xu Yao Tang Lingxue Zhang Xi Chen Xingyu Liang Ling Zhao Dehua Li |
| author_sort | Guilin Zhang |
| collection | DOAJ |
| description | Background: Postoperative pain is a significant yet inadequately managed complication following surgery, and auriculotherapy to alleviate acute postoperative pain (APP) and reduce the use of opioids remains controversial. Methods: We searched the MEDLINE, Web of Science, Embase, Cochrane Library, CINAHL Complete, and ClinicalTrials.gov from inception to January 23, 2024 for all randomized controlled trials (RCTs) of auriculotherapy in the treatment of APP. The extracted data underwent risk of bias assessment, meta-analysis, subgroup analyses, sensitivity analysis, meta-regression analysis, and evidence rating. Results: A total of 24 studies involving 2131 patients were included in the meta-analysis. Low-quality evidence indicated that auriculotherapy was effective in reducing pain intensity at 24 [MD(95 %CI)=-0.64(-1.09, −0.19), I2=77 %, P＜0.01], 48 [MD(95 %CI)=-0.49(-0.97, 0.00), I2=71 %, P=0.05], and 72 [MD(95 %CI)=-0.80(-1.32, −0.28), I2=52 %, P＜0.01] hours after surgery, while moderate-quality evidence showed a decrease in total opioid consumption [MD(95 %CI)=-24.41 OME (-38.28, −10.54), I2=95 %, P＜0.01]. However, no significant effects were observed in reducing postoperative nausea or vomiting [RR(95 %CI)=0.61(0.32, 1.16), I2=71 %, P=0.13; RR(95 %CI)=0.32(0.09, 1.18), I2=71 %, P=0.09; RR (95 %CI)=0.34(0.11, 1.06), I2=28 %, P=0.06; for postoperative nausea and vomiting (PONV), postoperative nausea or postoperative vomiting respectively], with evidence ranging from moderate to very low. Additionally, two RCTs found that auriculotherapy could delay the time to the first request for analgesia. Conclusions: The summary estimates indicate that auriculotherapy may be beneficial in reducing APP and opioid consumption in specific surgeries based on low-to-moderate quality evidence. However, high-quality RCTs are still further studied in different surgical populations. Systematic Review Registration: PROSPERO database, CRD42024506989. |
| format | Article |
| id | doaj-art-004cf1bf157641018776e599079cd774 |
| institution | Kabale University |
| issn | 0965-2299 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
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| series | Complementary Therapies in Medicine |
| spelling | doaj-art-004cf1bf157641018776e599079cd7742025-01-30T05:12:50ZengElsevierComplementary Therapies in Medicine0965-22992025-03-0188103112The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysisGuilin Zhang0Guixing Xu1Yao Tang2Lingxue Zhang3Xi Chen4Xingyu Liang5Ling Zhao6Dehua Li7Department of Acupuncture-Moxibustion and Rehabilitation, Hospital of Chengdu University of TCM, Chengdu, Sichuan 610072, China; College of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, ChinaDepartment of Acupuncture-Moxibustion and Rehabilitation, Hospital of Chengdu University of TCM, Chengdu, Sichuan 610072, China; College of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China; General Hospital of Western Theater Command, Chengdu, Sichuan 610031, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, ChinaDepartment of Acupuncture-Moxibustion and Rehabilitation, Hospital of Chengdu University of TCM, Chengdu, Sichuan 610072, China; Correspondence to: Postal address: Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-qiao Road, Chengdu, Sichuan 610072, China.Background: Postoperative pain is a significant yet inadequately managed complication following surgery, and auriculotherapy to alleviate acute postoperative pain (APP) and reduce the use of opioids remains controversial. Methods: We searched the MEDLINE, Web of Science, Embase, Cochrane Library, CINAHL Complete, and ClinicalTrials.gov from inception to January 23, 2024 for all randomized controlled trials (RCTs) of auriculotherapy in the treatment of APP. The extracted data underwent risk of bias assessment, meta-analysis, subgroup analyses, sensitivity analysis, meta-regression analysis, and evidence rating. Results: A total of 24 studies involving 2131 patients were included in the meta-analysis. Low-quality evidence indicated that auriculotherapy was effective in reducing pain intensity at 24 [MD(95 %CI)=-0.64(-1.09, −0.19), I2=77 %, P＜0.01], 48 [MD(95 %CI)=-0.49(-0.97, 0.00), I2=71 %, P=0.05], and 72 [MD(95 %CI)=-0.80(-1.32, −0.28), I2=52 %, P＜0.01] hours after surgery, while moderate-quality evidence showed a decrease in total opioid consumption [MD(95 %CI)=-24.41 OME (-38.28, −10.54), I2=95 %, P＜0.01]. However, no significant effects were observed in reducing postoperative nausea or vomiting [RR(95 %CI)=0.61(0.32, 1.16), I2=71 %, P=0.13; RR(95 %CI)=0.32(0.09, 1.18), I2=71 %, P=0.09; RR (95 %CI)=0.34(0.11, 1.06), I2=28 %, P=0.06; for postoperative nausea and vomiting (PONV), postoperative nausea or postoperative vomiting respectively], with evidence ranging from moderate to very low. Additionally, two RCTs found that auriculotherapy could delay the time to the first request for analgesia. Conclusions: The summary estimates indicate that auriculotherapy may be beneficial in reducing APP and opioid consumption in specific surgeries based on low-to-moderate quality evidence. However, high-quality RCTs are still further studied in different surgical populations. Systematic Review Registration: PROSPERO database, CRD42024506989.http://www.sciencedirect.com/science/article/pii/S0965229924001006Acute postoperative painAuriculotherapyMeta-analysisMultimodal analgesiaRandomized trial |
| spellingShingle | Guilin Zhang Guixing Xu Yao Tang Lingxue Zhang Xi Chen Xingyu Liang Ling Zhao Dehua Li The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis Complementary Therapies in Medicine Acute postoperative pain Auriculotherapy Meta-analysis Multimodal analgesia Randomized trial |
| title | The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis |
| title_full | The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis |
| title_fullStr | The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis |
| title_full_unstemmed | The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis |
| title_short | The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis |
| title_sort | analgesic effectiveness of auriculotherapy for acute postoperative pain a systematic review and meta analysis |
| topic | Acute postoperative pain Auriculotherapy Meta-analysis Multimodal analgesia Randomized trial |
| url | http://www.sciencedirect.com/science/article/pii/S0965229924001006 |
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